Most of the iron in legume seeds is stored in ferritin located in the amyloplast, which is used during seed germination. However, there is a lack of information on the regulation of iron by phytoferritin. In this study, soluble and insoluble forms of pea (Pisum sativum) seed ferritin (PSF) isolated from dried seeds were found to be identical 24-mer ferritins comprising H-1 and H-2 subunits. The...

Ferritins are recognized as key players in the iron storage and detoxification processes. Iron acquisition in the case of pathogenic bacteria has long been established as an important virulence mechanism. Here, we report a 3.0 Å crystal structure of a ferritin, annotated as Bacterioferritin B (BfrB), from Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis that continues to be...

abstract background phenyl ketonuria (pku) is a congenital metabolic disease. irreversible brain damage is the result of phenyl alanin accumulation, so its amount should be restricted in patients diet. in their diet, trace elements such as hem iron, folic acid, vitamin b12 and, etc are also limited, and could represent anemia. in this study, the frequency of anemia in pku patients in yazd was i...

The iron redox cycle in ferritins is not completely understood. Bacterioferritins are distinct from other that they contain haem groups. It acknowledged the two motifs bacterioferritins, di-nuclear ferroxidase centre and B group, play key roles opposing processes, sequestration mobilisation, respectively, processes independent. Herein, we show Escherichia coli bacterioferritin, there an electro...