Background: Femoral neck fracture is one of the most common fractures in elderly. Proximal femur elderly patients considered a severe morbidity which has negative impact on life expectancy and quality life. Aim this study was to find correlation cortical thickness index (CTI) SI toward bone density (BMD) female over 60 years age with femoral fracture.Methods: This an observational cross-section...

Purpose: In this study, the main goal was to determine the correlation between the thickness of cerebral cortex and the severity of cognitive disorder in Alzheimer's disease Materials and method: Twenty patients diagnosed with Alzheimer’s disease with mean age of 72.95 year(14 women and 6 men) and Ten Cognitively normal (CN) subjects with mean age of 70.50 year( 7 women and 3 men) were include...

Parathyroid hormone (PTH) restores bone mass to the osteopenic skeleton, but significant questions remain as to the underlying mechanisms. The receptor for advanced glycation end products (RAGE) is a multiligand receptor of the immunoglobulin superfamily; however, recent studies indicate a role in bone physiology. We investigated the significance of RAGE to hormone-induced increases in bone by ...

A mutation in LRP5 (low-density lipoprotein receptor-related protein 5) has been shown to increase bone mass and density in humans and animals. Transgenic mice expressing the LRP5 mutation (G171V) demonstrate an increase in bone mass as compared to non-transgenic (NTG) littermates. This study evaluated LRP5 gene and gender-related influences on the structural and biomechanical strength properti...

background: abdominal circumference (ac), biparietal diameters (bpd) and femoral length (fl) are now the main parameters used to obtain estimated fetal weight (efw). although the role of soft tissue parameters in determining fetal weight was proved but clinical attention to mid-thigh soft tissue thickness (stt) is limited. objective: to find the impression of stt on birth weight (bw) and repres...

AIMS/INTRODUCTION Previous studies have reported osteoporosis measured by dual-energy X-ray absorptiometry in younger patients with type 1 diabetes. Limitations of 2-D imaging, however, limit the precision of dual-energy X-ray absorptiometry for the measurement of bone mineral density and bone strength. MATERIALS AND METHODS Three-dimensional quantitative computed tomography was used to calcu...

BACKGROUND Hip fracture risk rises 100 to 1000-fold over 60 years of ageing. Loss of resistance to bending is not a major feature of normal ageing of the femoral neck. Another cause of fragility is local buckling or elastic instability. Bones adapt to their local experience of mechanical loading. The suggestion that bipedalism allows thinning of the underloaded superolateral femoral neck cortex...

MOTIVATION Cortical bone is an important contributor to bone strength and is pivotal to understand the etiology of osteoporotic fractures and the specific mechanisms of antiosteoporotic treatment regimen. 3D computed tomography (CT) can be used to measure cortical thickness, density, and mass in the proximal femur, lumbar vertebrae, and distal forearm. However, the spatial resolution of clinica...