The overcoming of catabolite repression, in bioinsecticides production by sporeless Bacillus thuringiensis strain S22 was investigated into fully controlled 3 L fermenter, using glucose based medium. When applying adequate oxygen profile throughout the fermentation period (75% oxygen saturation), it was possible to partially overcome the catabolite repression, normally occurring at high initial...

Anaerobic fermentation processes for the production of a succinate-rich animal feed supplement from raw whey were investigated with batch, continuous, and variable-volume fed-batch cultures with Anaerobiospirillum succiniciproducens. The highest succinate yield, 90%, was obtained in a variable-volume fed-batch process in comparison to 80% yield in a batch cultivation mode. In continuous culture...

BACKGROUND Mannosylerythritol lipids (MEL) are glycolipids with unique biosurfactant properties and are produced by Pseudozyma spp. from different substrates, preferably vegetable oils, but also sugars, glycerol or hydrocarbons. However, solvent intensive downstream processing and the relatively high prices of raw materials currently used for MEL production are drawbacks in its sustainable comm...

A multi-objective optimization formulation that reflects the multi-substrate optimization in a multi-product fermentation is proposed in this work. This formulation includes the application of epsilon-constraint to generate the trade-off solution for the enhancement of one selective product in a multi-product fermentation, with simultaneous minimization of the other product within a threshold l...

-----------------------------------------------------ABSTRACT----------------------------------------------------Xanthan gum is a natural polysaccharide having an industrial importance. It is commonly called as heteropolysaccharide which is produced by Xanthomonas campestris. In the present investigation Xanthan gum fermentation by local isolates of Xanthomonas campestris NRRL-B-1449 from sugar...

This work presents the development of an unstructured kinetic model incorporating the differing degrees of product inhibition on the kinetic rates of recombinant Zymomonas mobilis fermentation. A mechanism for the inhibition of two competing substrates cellular uptake via membrane transport is proposed. The model was utilized in a nonlinear model predictive control (NMPC) algorithm to control p...