The clinical and genetic relationships of febrile seizures and the generalized epilepsies are poorly understood. We ascertained a family with genealogical information in 2000 individuals where there was an unusual concentration of individuals with febrile seizures and generalized epilepsy in one part of the pedigree. We first clarified complex consanguineous relationships in earlier generations...

BACKGROUND Autism spectrum disorder (ASD) is a heterogeneous disorder characterized not only by deficits in communication and social interactions but also a high rate of co-occurring disorders, including metabolic abnormalities, gastrointestinal and sleep disorders, and seizures. Seizures, when present, interfere with cognitive development and are associated with a higher mortality rate in the ...

Previous studies reported that the proline-rich transmembrane protein 2 (PRRT2) gene was identified to be related to paroxysmal kinesigenic dyskinesia (PKD), infantile convulsions with PKD, PKD with migraine and benign familial infantile epilepsy (BFIE). The present study explores whether the PRRT2 mutation is a potential cause of febrile seizures, including febrile seizures plus (FS+), general...

Design: Case control study, Setting: Pediatric department of a tertiary care teaching hospital, Participants: Cases were children of age group 6 months to 5 years presenting with simple febrile seizures. Controls were children of same age group presenting with short febrile illness without any seizures, Materials and Methods: In this study, cases 101 children with febrile seizures and 101 febri...

OBJECTIVES To compare the incidence of febrile seizures in children hospitalized for influenza A infection with parainfluenza and adenovirus infection and to examine the hypothesis that children hospitalized for influenza A (variant Sydney/H3N2) during the 1998 season in Hong Kong had more frequent and refractory seizures when compared with other respiratory viruses, including the A/Wuhan H3N2 ...

BACKGROUND Febrile convulsions, or febrile seizures, are frequently encountered in paediatrics, and despite often being self limiting, these seizures strike fear in the hearts of patients' carers. OBJECTIVE This article reviews the assessment and management of febrile seizures in children. DISCUSSION The initial assessment of a child who convulses with fever should be directed at finding a ...

With a worldwide incidence as high as 6.7% of children, febrile seizures are one of the most common reasons for seeking pediatric care, but the mechanisms underlying generation of febrile seizures are poorly understood. Febrile seizures have been suspected to have a genetic basis, and recently, mutations in GABAA receptor and sodium channel genes have been identified that are associated with fe...

how to cite this article: esmaili gourabi h, bidabadi e, cheraghalipour  f, aarabi  y, salamat f. febrile seizure: demographic features and causative factors. iran j child neurol autumn 2012; 6(4):33-37. abstract objective because of geographical and periodical variation, we prompted to determine the demographic features and causative factors for febrile seizure in rasht. materials & methods in...