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Bordetella pertussis is the causative agent of whooping cough. This pathogenic bacterium can obtain the essential nutrient iron using its native alcaligin siderophore and by utilizing xeno-siderophores such as desferrioxamine B, ferrichrome, and enterobactin. Previous genome-wide expression profiling identified an iron repressible B. pertussis gene encoding a periplasmic protein (FbpABp). A pre...
Fibronectin (Fn) is an approximately 450 kDa glycoprotein that consists of 12 type I, 2 II, and 15–17 III modules. Fibrillation Fn important for tissue reconstitution wound healing. We previously reported Clostridium perfringens produces several Fn-binding proteins (Fbps), two which, FbpA FbpB, bind to III1-C (a fragment derived from the carboxyl-terminal two-thirds first-type module). Dermatop...
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