Nontraumatic rapid growing giant fat necrosis of the breast mimicking breast tumors is a rare clinical manifestation. The imaging features of the fat necrosis which range from benign to malign findings may be better explained with associated aetiology. The present paper reports a 54-year old woman with a rapid growing, fibrous, and hard giant mass originating in the subareolar region of the lef...

Methods: A 27-year-old female underwent bilateral breast fat grafting (abroad) in a foreign centre which produced symptomatic palpable lumps. A 3 year post procedure MRI showed bilateral discrete fat necrosis and oil capsular lumps I, largest being 3 by 5 cm. She underwent debridement of bilateral fat necrosis using a microdebrider (Medtronic). Histology confirmed fat necrosis with reactive chr...

Methods: A 27-year-old female underwent bilateral breast fat grafting (abroad) in a foreign centre which produced symptomatic palpable lumps. A 3 year post procedure MRI showed bilateral discrete fat necrosis and oil capsular lumps I, largest being 3 by 5 cm. She underwent debridement of bilateral fat necrosis using a microdebrider (Medtronic). Histology confirmed fat necrosis with reactive chr...

We report the case of an infant with diffuse subcutaneous fat necrosis following birth asphyxia who had hypercalcemia and the rare complication of venous calcification. The clinical and radiologic findings resolved over 5 months. The disease is characterized by the presence of painless subcutaneous nodules, mainly over bony prominences, possibly associated with hypercalcemia and calcification. ...

Acute pancreatitis can result in retroperitoneal fat necrosis, typically occurring in the peripancreatic region, with extension into the transverse mesocolon, omentum and mesenteric root. When evaluated with contrast enhanced computed tomography (CECT), acute peripancreatic post necrotic collections typically become lower in attenuation over time, and often appear as homogeneous fluid collectio...

Breast reconstruction is now a part of the overall treatment of breast cancer. Its main drawback is rather the suspicion to conceal any probable recurrence. Fat necrosis is a particularly important finding because it can be mistaken for a local recurrence. Alternatively, local recurrences may be dismissed as areas of fat necrosis. Fat necrosis is a relatively minor complication of TRAM flap bre...

Fat necrosis of the breast is a well-recognised complication of unfractionated heparin. The following is a case of fat necrosis due to low-molecular-weight heparin in a 91-year-old woman admitted to hospital with unstable angina.

UNLABELLED The case is a 34-year-old woman with long-standing type 1 diabetes mellitus with existing follow-up in the outpatient clinic at the Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism, UHCW. She had maintained good glycaemic control and glycaemic stability with basal bolus regimen for many years. She had not developed any diabetes-related complications and ...

To assess modification of thioacetamide-induced hepatotoxicity in mice fed a high-fat diet, male C57BL/6J mice were fed a normal rodent diet or a high-fat diet for 8 weeks and then treated once intraperitoneally with thioacetamide at 50 mg/kg body weight. At 24 and 48 hours after administration, massive centrilobular hepatocellular necrosis was observed in mice fed the normal rodent diet, while...