Conducting organic syntheses in microfluidic chips allows studying and optimising chemical reactions at minimal time-scales and resource consumption. Herein, we describe a multi-channel microdroplet chip, which allows fast and directed dispensing of reactants into individual droplets in a segmented flow. This gives access to study the reaction progress in situ via surface-enhanced Raman spectro...

Isothiocyanates are versatile starting materials for a wide range of chemical reactions. However, their high nucleophilic susceptibility means they are best prepared and used immediately. We report here on a flow platform for the fast and efficient formation of isothiocyanates by the direct conversion of easily prepared chloroximes. To expedite this chemistry a flow insert cartridge containing ...

The quadratic autocatalytic reaction forms a key step in number of chemical systems, and traveling waves are observed such systems. In this study, we investigate the effect complexation reactions on system. More precisely, under assumption that is fast relative to reaction, show governing system reduced two-component reaction-diffusion with density-dependent diffusivity. Further, numerical evid...

The chemical master equation (CME) is the exact mathematical formulation of chemical reactions occurring in a dilute and well-mixed volume. The reaction-diffusion master equation (RDME) is a stochastic description of reaction-diffusion processes on a spatial lattice, assuming well-mixing only on the length scale of the lattice. It is clear that, for the sake of consistency, the solution of the ...

The dynamical solution of a well-mixed, nonlinear stochastic chemical kinetic system, described by the Master equation, may be exactly computed using the stochastic simulation algorithm. However, because the computational cost scales with the number of reaction occurrences, systems with one or more "fast" reactions become costly to simulate. This paper describes a hybrid stochastic method that ...

Chemical processes like carbonation of concrete structures are driven by slow diffusion processes and fast reactions. This leads to the formation of relatively sharp reaction fronts, which move slowly through the material. Self-adaptive finite element methods provide a tool to automatically generate meshes locally fine enough to capture the reaction, while coarser meshes are sufficient in the b...

Nucleic acid templated reactions are enabled by the hybridization of probe-reagent conjugates resulting in high effective reagent concentration and fast chemical transformation. We have developed a reaction that harnesses cellular microRNA (miRNA) to yield the cleavage of a linker releasing fluorogenic rhodamine in a live vertebrate. The reaction is based on the catalytic photoreduction of an a...