Curcumin (diferuloylmethane) is a phytochemical with potent Objective: anti-inflammatory and anti-oxidant properties, and has therapeutic potential for the treatment of a range of inflammatory diseases, including osteoarthritis (OA). The aim of this study was to determine whether non-toxic concentrations of curcumin can reduce interleukin-1beta (IL-1β)-stimulated inflammation and catabolism in ...

Plasma vasopressin (VP) concentration is elevated in spontaneously hypertensive rats (SHRs) relative to their normotensive Wistar-Kyoto (WKY) controls. The possibility that this reflects altered responsiveness of the hypothalamo-neurohypophyseal system (HNS) in SHRs was examined by comparing VP release in response to acetylcholine from organ cultured HNS explants obtained from SHR and WKY donor...

In the present investigation, a micropropagation protocol has been developed for Vanilla borneensis Rolfe – critically endangered orchid through multiple shoot regeneration. Through in vitro regeneration from both nodal and tip explants, maximum (100%) induction was observed. The minimum time required bud observed (5–7 days) on medium supplemented with BAP (4.44 mM) + KIN (2.32 as compared to e...

Micropropagation of three genotypes of Indian mustard [Brassica juncea (L.) Czern.] using 7-days old seedling-derived transverse thin cell layer (tTCL) explants was accomplished. The genotype, explant source and addition of silver nitrate to the medium significantly influenced shoot bud induction. MS medium with 26.6 μM of 6-Benzylaminopurin (BAP) and 3.22 μM of 1-naphtaleneacetic acid (NAA) wa...

Batrachochytrium dendrobatidis, the causal agent of chytridiomycosis, is implicated in the global decline of amphibians. This chytrid fungus invades keratinised epithelial cells, and infection is mainly associated with epidermal hyperplasia and hyperkeratosis. Since little is known about the pathogenesis of chytridiomycosis, this study was designed to optimise the conditions under which primary...

PURPOSE There is mounting evidence that retinal ganglion cells (RGCs) require a complex milieu of trophic factors to enhance cell survival and axon regeneration after optic nerve injury. The authors' goal was to examine the contribution of components of a combination of hormones, growth factors, steroids, and small molecules to creating a regenerative environment and to determine if any of thes...

The present study was conducted to induce callus from different in vitro grown seedling explants of shoot, root and leaf segments in order to develop shoot buds and rooting from callus. The sterilized seeds were cultured on Murashige and Skoog medium, and then the explants were cultured from seedling and transferred to an MS medium supplemented with different concentrations of BAP, kinetin, NAA...

Fatty acids are considered metabolic intermediaries, although new facts indicate they also work as signaling molecules with different roles in the immune response. Based on that, this study, we investigated anti-inflammatory effects of n-3 polyunsaturated fatty (PUFAs) eicosapentaenoic acid (EPA), docosahexaenoic (DHA), and α-linolenic (LNA) ex vivo bovine endometrial explants. For this, two gr...

Rossi, Noreen F., and William H. Beierwaltes. Nitric oxide modulation of ETB receptor-induced vasopressin release by rat and mouse hypothalamo-neurohypophyseal explants. Am J Physiol Regul Integr Comp Physiol 290: R1208–R1215, 2006. First published December 15, 2005; doi:10.1152/ajpregu.00701.2005.—Endothelin (ET) peptides stimulate vasopressin (AVP) secretion via ETB receptors at hypothalamic ...