The optical instruments design has become an earnest demand towards the arrival of an aging society. It is necessary to measure the vision difference that can be permitted before the rivalry occurs for elderly people. In this study, we measured the limit of vision fusion in the normal vision and the cataract experiencing vision which is used to simulate the elderly vision. The result shows that...

This study reports the first demonstration of a marked reduction in alpha-crystallin chaperone activity in an experimental model of cataract, and the study implicates activation of the cysteine protease calpain II (EC 3.4.22.17) as the in vivo protease responsible for decreased chaperone activity. Chaperone activity of normal alpha-crystallin from lenses of young rats was assayed by measuring a...

purpose : cataract is one of the most common diseases of older ages and, at present, the leading cause of avoidable blindness in the world. along with the population growth, the rate of cataract surgeries is increasing in most countries worldwide. the number of cataract operations per million population per year is known as the cataract surgery rate (csr) and is one of the indicators introduced...

Objectives To investigate the potential protective effects of sesamol in an experimental cataract model. Materials and Methods Twenty-one Spraque Dawley rat pups were randomly assigned into three groups, seven rats in each. All the rats except for those in the control group were injected subcutaneously with a single dose of sodium selenite on postpartum day 9. On days 10-14, rats in the sham ...

Introduction: Cataract is a frequent ocular pathology in the world. The aim of our work was to study contribution mode B ultrasound diagnostic and therapeutic management cataracts radiology department medical clinic Marie Curie Bamako. Material Methods: This prospective, descriptive carried out imaging over period 2 years. Ocular examinations were performed exclusively with B-mode scanner by se...

purpose: to determine the incidence and risk factors associated with glaucoma following congenital cataract surgery (ccs) in children under age of 15 methods: this prospective cohort (since 2006) consisted of children less than 15 years of age who underwent cataract surgery with or without intraocular lens (iol) implantation. the role of the following factors on the development of glaucoma afte...

background: decreasing intraocular pressure (iop) and preventing the iop rising during cataract surgery, is one of the most important factors in successful cataract surgery. this study was conducted to investigate the effects of intravenous lidocaine on iop in cataract surgery under sedation. methods: the study was a double blind controlled trial which firstly, the patient’s iop was measured. t...

Purpose: Age-related cataract is the leading cause of blindness worldwide. Variants in EPHA2 gene increase disease risk, and its knockout mice causes cataract. We investigated whether age, sex, genetic background, risk factors for age-related cataract, Epha2 genotype influence Epha2-related development mice. Methods: Cataract was monitored Epha2+/+, Epha2+/−, Epha2−/− (Epha2Gt(KST085)Byg) on C5...

Background: The majority of dogs with diabetes mellitus develop blinding mature cataracts through the action of the enzyme aldose reductase producing sorbitol with osmotic action drawing water into the lens thus causing opacification. Here we evaluate the use of OcuGLOTM a formulation including the aldose reductase inhibitor alpha lipoic acid, grapeseed extract, carotenoids, omega-3-fatty acids...