where v is the total exchanged volume, V is the patient's blood volume and e is the transcendental number, base of the natural logarithm. However, he later stated that his formula was not correct because it did not take into consideration the difference between the patient's haematocrit and that of the transfused blood. Moreover, according to others, even when the two haematocrits happen to be ...

OBJECTIVES To assess the effectiveness of intensive phototherapy in reducing the need for exchange transfusion and the duration of phototherapy. METHODS The prospective study with historical controls was conducted at Cairo University Paediatric Hospital, from February to July 2012, and comprised 360 newborns with indirect hyperbilirubinaemia. The 183 subjects were treated with Bilisphere 360 ...

The changes in plasma thyroid hormone concentration were studied during exchange transfusion performed for haemolytic disease. 24 transfusions were performed using blood preserved with acid-citrate and dextrose and in 11 cases 10 or 50 mug glucagon was added to the donor blood. Plasma tri-iodothyronine (T3), thyroxine (T4), thyrotropin (TSH), thyroid hormone binding capacity, and free thyroxine...

strict surgical asepsis, the use of transparent catheter (polyvinyl feeding tube with a rounded end and side holes) for umbilical catheterization was strongly suggested, as it enabled easy identification of the air bubbles that can cause of air embolism if pushed into the circulation. The clearance of blocked catheters (clots in the circulation) using pressure was strongly reprehended. In situa...

Automated method for exchange transfusion Sir, Philpott and Banerjee (Archives, 1972) are to be congratulated on their method of exchange transfusion using a two-channel Holter pump. Many have been interested in this technical problem, and the Holter pump provides an acceptable solution. The pumping rate of the machine is accurate to ±3%. More importantly, the discrepancy between the flow rates...

BACKGROUND Severe polycythaemia in the neonate may produce symptoms due to hyperviscosity and may be associated with serious complications. Partial exchange transfusion will reduce the packed cell volume. OBJECTIVE To determine whether partial exchange transfusion in term infants with polycythaemia (symptomatic and asymptomatic) is associated with improved short and long term outcomes. SEAR...

Background: Due to multiple roles of albumin in the body, injection of its medicinal product as one of the therapeutic or management strategies under conditions such as severe bleeding, burns, liver failure, and neonatal hemolytic diseases is on the physicians' agenda. Considering that albumin is the most abundant plasma protein, designing an appropriate method to purify it is highly important....

During 23 exchange transfusions, the granulocytes from 27 donors and 16 newborn infants were tested for opsonic activity and granulocyte function by the nitrobluetetrazolium test. Granulocyte function in a newborn baby receiving an exchange transfusion can be altered positively or negatively, depending on the quality of the donor's blood. If exchange transfusion is used in the management of neo...

A fatal case of neonatal cytomegalovirus (CMV) infection attributed to exchange transfusion is described. The incidence of CMV transmission by exchange and other neonatal transfusion was studied, and the use of CMV antibody-free blood for these procedures was shown to be effective in preventing CMV infection in neonates.

Partial exchange transfusion with a cell-free hemoglobin (Hb) polymer during transient middle cerebral artery occlusion (MCAO) reduces infarct volume but fails to increase blood flow, as might be expected with the induced decrease in hematocrit. In ischemic brain, endothelin antagonists are known to produce vasodilation. In nonischemic brain, pial arterioles constrict after Hb exchange transfus...