BACKGROUND Auditory-evoked potentials have proven useful in the objective evaluation of sound encoding at different stages of the auditory pathway (brainstem and cortex). Yet, their utility for use in clinical assessment and empirical research relies critically on the precision and test-retest repeatability of the measure. PURPOSE To determine how subcortical/cortical classes of auditory neur...

The neurophysiological basis of variability in the latency of evoked neural responses has been of interest for decades. We describe a method to identify white matter pathways that may contribute to inter-individual variability in the timing of neural activity. We investigated the relation of the latency of peak visual responses in occipital cortex as measured by magnetoencephalography (MEG) to ...

Information processing and coding were analysed in dissociated hippocampal cultures, grown on multielectrode arrays. Multisite stimulation was used to activate different neurons and pathways of the network. The neural activity was binned into firing rates and the variability of the firing of individual neurons and of the whole population was analysed. In individual neurons, the timing of the fi...

An effective physiological pain assessment method that complements the gold standard of self-report is highly desired in pain clinical research and practice. Recent studies have shown that pain-evoked electroencephalography (EEG) responses could be used as a readout of perceived pain intensity. Existing EEG-based pain assessment is normally achieved by cross-individual prediction (i.e., to trai...

Pain is a complex experience with sensory, emotional and cognitive aspects. It also includes a sympathetic response that can be captured by measuring the electrodermal activity (EDA). The present study was performed to investigate which brain areas are associated with sympathetic activation in experimental pain; an issue that has not been addressed with fMRI (functional magnetic resonance imagi...