OBJECTIVES To compare the clinical efficacy, pharmacokinetic profiles and safety of once-daily dosing (ODD) and multiple daily dosing (MDD) of gentamicin in hospitalized Indian children. PATIENTS AND METHODS Four hundred children admitted to our hospital were studied prospectively. The patients were randomized to ODD or MDD groups alternately. The primary outcomes were: (i) a good clinical ou...

BACKGROUND High bilirubin level is toxic to developing brain and auditory system but the current debate surrounds the toxicity of bilirubin in healthy term infants. METHODS Longitudinal observational study to find BERA abnormalities in term newborns with isolated hyperbilirubinemia of 20 mg/dL and more and to follow up babies at 3 months to find out about the reversibility in BERA abnormaliti...

UNLABELLED Exposure to noise has a harmful effect on the auditory health of workers. AIM The main goal of this paper was to establish the role of pure-tone audiometry and evoked transient otoacoustic emissions in the detection of small temporary auditory changes after exposure to high sound pressure levels. STUDY DESIGN A cross-sectional cohort study. MATERIAL AND METHODS 30 otologically ...

Background: the suppression effect with contralateral white noise observed in the brainstem auditory evoked potential can be influenced by the efferent auditory system. Aim: to evaluate the suppression effect with contralateral white noise in the Brainstem Auditory Evoked Potential of individuals with normal hearing. Methods: 25 individuals, ranging in age from 18 to 30 years, of both genders, ...