The effects of the crude, methanol, hexane TLC and acetone extractable portion of strebulus as per on frog's heart and smooth muscle of rabbit were studied. The different extracts of S. asper showed a stimulant effect on frog's heart while the crude and methanol extracts showed not much alteration in the peristaltic activity of smooth muscle or rabbit. Methanol, hexane and acetone extractable p...

A simple, selective, precise and accurate Reverse Phase High Pressure LiquidChromatographic (RPHPLC) method was developed and validated for the simultaneousestimation ofgatifloxacin and difluprednate in pharmaceutical dosage forms.The method was validated for accuracy, specificity, linearity and robustness asper the ICH guidelines.Binary elution at a flow rate of 1.0 mL per min was employed onE...

*The original version of this paper was written for the Office of ASPER of the U.S. Department of Labor in 1975. This is a revision of ‘Unemployment insurance as a social insurance program’ presented at the ISPE Conference on Social Insurance held near Tokyo. Japan in May 1977. I would like to thank participants at this conference, M.A. Baily, G.S. Fields and the referees for helpful comments. ...

INTRODUCTION Snakebite accidents are an important health problem in rural areas of tropical countries worldwide, including Costa Rica, where most bites are caused by the pit-viper Bothrops asper. The treatment of these potentially fatal accidents is based on the timely administration of specific antivenom. In many regions of the world, insufficient health care systems and lack of antivenom in r...

BACKGROUND Sonchus asper (L.) Hill, (Asteraceae) is used in Pakistan as a traditional ("folk") medicine for the treatment of hormonal disorders and oxidative stress. The present study was aimed to evaluate the efficacy of Sonchus asper (L.) Hill, (Asteraceae) methanolic extract (SAME) on hormonal dysfunction in thyroid tissue after carbon tetrachloride (CCl4)-induced oxidative stress. METHODS...

A new generation product made from bamboo strips, known as laminated bamboo, has gained importance. The objective of this research was to experiment the effect of three factors on the mechanical property of laminated bamboo. The interested factors for experimental design were (A) four bamboo species, namely Bambusa blumeana Schultes (Pai See Suk), Dendrocalamus asper Backer (Pai Tong), Dendroca...

A new myotoxic phospholipase A2 was isolated from the venom of the arboreal snake Bothriechis schlegelii (formerly Bothrops schlegelii) from Costa Rica, by ion-exchange chromatography on CM-Sephadex. B. schlegelii myotoxin I is a basic protein (pI > 9.3) with a subunit molecular weight of 15 kDa, which migrates as a dimer in sodium dodecyl sulfate-polyacrylamide gel electrophoresis under nonred...

Curr Res Cardiol Vol 3 No 4 Winter 2016 117 St Boniface Hospital, Asper Clinical Research Institute and Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada, Department of Pharmacology and Therapeutics, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, ...

We report a case of snakebite in which envenomation was manifested through impairment of the visual field. The patient, a 46-year-old man, was bitten on the right thumb by Bothrops lanceolatus. Treatment with a specific equine antivenom (Bothrofav) was administered one hour after the bite. With the exception of fang marks, the results of a clinical examination, particularly the neurologic compo...