JNCI Vol. 103, Issue 13 | July 6, 2011 In this issue of the Journal, Petracci et al. (1) present a model to estimate the degree of benefit in terms of breast cancer risk reduction that may be achieved with risk factor modification. By how much would breast cancer risk change over a 10-year period for a 45-yearold Italian woman making changes in modifiable risk factors such as exercise, weight, ...