Clear cell acanthoma or Degos' acanthoma is a distinct disease concerning its clinical, histopathological, and immunohistochemical features. Its pathologic nature - whether neoplastic or reactive - is still under dispute among researchers. The disease shows a chronic course and often presents with a single papulonodular lesion on the lower limbs of adults. However, cases with multiple lesions, ...

We present the case of a 59-year-old female with multiple squamous neoplasms, including keratoacanthomas, well-differentiated cell carcinomas, and prurigo nodules. The patient developed dozens lesions progressively over course few years. Keratoacanthomas can be challenging to distinguish from carcinomas; this presence numerous poses major challenge diagnosing managing condition. pathogenesis, c...

Eruptive Keratoacanthomas AssociatedWith Leflunomide The keratoacanthoma (KA) is a rapidly growing, welldifferentiated epidermal neoplasm that may be locally invasive or may spontaneously resolve. Most often, KA presents as a solitary lesion; however,multipleKAs canbe seen in various syndromes, including Muir-Torre syndrome, the autosomal dominant Ferguson-Smith syndrome, and Grzybowskitype eru...

Assessment of volcanic hazards is necessary for risk mitigation. Typically, hazard assessment is based on one or a few, subjectively chosen representative eruptive scenarios, which use a specific combination of eruptive sizes and intensities to represent a particular size class of eruption. While such eruptive scenarios use a range of representative members to capture a range of eruptive sizes ...

Xanthomas are localized lipid deposits in the skin, tendons and subcutaneous tissue associated with lipid abnormality. The hyperlipidemia responsible for this disorder can be caused by a primary genetic defect, a secondary disorder, or both. That kind of skin exanthema may be the first signal of cardiovascular risk. We present a 24-year-old woman with a skin eruption that had appeared a few mon...

The submarine volcanic eruption occurring near El Hierro (Canary Islands) in October 2011 provided a unique opportunity to determine the effects of such events on the microbial populations of the surrounding waters. The birth of a new underwater volcano produced a large plume of vent material detectable from space that led to abrupt changes in the physical-chemical properties of the water colum...

efficacy. These lesions are rarely selflimiting, and recurrences are common. We describe a 25-year-old woman with no relevant history who consulted for asymptomatic, flesh-colored papules of 1-2 mm, distributed on the anterior area of the neck and neckline (Figure 1). The symptoms started 10 years earlier on the lower eyelids, gradually spreading to the abdomen, neck, and neckline, with outbrea...