To evaluate the effects of endotoxin on the morphology of the equine mesenteric vasculature, each of two thoroughbred horses were given two intravenous injections (24 h apart) of a sublethal dose of endotoxin (10 microg/kg). Each injection produced results similar to those of clinical cases of equine colic with obstructive nature of the loop of bowel: diarrhoea within 2 h after administration, ...

BACKGROUND Little is known about lay understanding and decision making in response to colic. Horse-owners/carers are key to identifying colic and initiating veterinary intervention. Understanding how owners think and act in relation to colic could assist veterinary surgeons in tailoring information about colic with the aim of improving colic outcomes. METHODS A mixed methods approach was empl...

REASONS FOR PERFORMING STUDY A minority of equine colic cases prove fatal unless treated surgically; however, few studies have considered long-term survival and complication rates, and few have attempted to identify factors that might affect outcomes. Such information is required for owners and veterinary surgeons to make informed decisions about the most appropriate treatment for individual ca...

Intragastric pH profiles in sick newborn foals often differ from those seen in healthy animals. Within the population of diseased foals, there exists wide variation in profile, related primarily to type and severity of illness. The increase in intragastric pH after H2 receptor antagonism (ranitidine, 2.0 mg/kg IV) was predictable in healthy animals but was inconsistent in many diseased foals. I...

Just as the term colic describes a clinical presentation and encompasses a large number of disorders, gastroduodenal ulceration describes a clinical finding, the cause of which is likely to be multifactorial and different from case to case. Within the umbrella term gastroduodenal ulceration are included symptomatic and asymptomatic cases, focal or multifocal ulceration involving the squamous or...

• In a second study, prevalence of tapeworm infection in 157 horses was randomly evaluated at necropsy during a 12-month period. Anoplocephala perfoliata was identified in 27% of the horses, exceeding what fecal testing would indicate in many herds. Horses <2 years of age, perhaps due to immunologic susceptibility, were at greater risk of tapeworm infection than adult horses. The geometric mean...

To study clinical and histopathological changes occur within the first 12 hours of strangulating obstruction of the small intestine in equine, twenty five adult donkeys were used in an experimental study. Strangulation obstruction of the small intestine was performed for 3, 6, 9 and 12 hours, respectively. Clinical examination was done before surgery and at 3 hours intervals postoperatively. Af...