Epilepsy is the third most common chronic brain disorder which is characterized by an enduring predisposition to generate seizures. Mesial Temporal Lobe Epilepsy (MTLE) is the most common type of refractory epilepsy. Increasing evidence indicates that neuroinflammation plays a critical role in the pathogenesis of MTLE. Hundreds of micro-RNAs have been found to be abnormally expressed in epilept...

background: epilepsy comprised the highest proportion of neurological problem of childhood stage, which observed mostly in the first decade of life. the dramatic effect of having a seizure in the classroom can be very traumatic for any child. the knowledge and attitude of teachers toward epilepsy have a direct impact on the life of students with epilepsy. methods: a cross-sectional descriptive ...

background: we investigated the effects of carbamazepine (cbz) on semen parameters in men with newly diagnosed epilepsy, by performing semen analysis before starting any antiepileptic drugs, and then after starting cbz, to determine the role and effects of cbz in creating abnormalities in sperm analysis in these patients. methods: in this prospective study, eight male patients 20-40 years of ag...

background: imaging studies performed in research centers suggest a high prevalence of brain structural abnormalities in patients with epilepsy. however, the results of research studies may not be directly applicable to general clinic, because they may perform on patients with high probability of cerebral abnormalities. on the other hand, more advanced modalities are likely to be used in resear...

how to cite this article: inaloo s, katibeh p. an epidemiologic study of 389 children with epilepsy in southern iran.iranian journal of child neurology2011;5(4):15-20 objective approximately 4% of the world's population experience one or more febrile seizures during their lifetime, and 0.5-1% of the population has active epilepsy.less than one-third of the reported seizures are categorized as e...

Lamotrigine (LTG), a newly developed antiepileptic drug (AED), is efficacious in treating refractory epilepsy. This study was designed to evaluate the efficacy and safety of LTG as add-on therapy in 40 children with refractory epilepsy. The trial was an open-labeled prospective study in children with drug-resistant epilepsy aged

Epilepsy is a chronic clinical syndrome of brain function which is caused by abnormal discharge of neurons. MicroRNAs (MiRNAs) are small noncoding RNAs which act post transcriptionally to regulate negatively protein levels. They affect neuroinflammatory signaling, glial and neuronal structure and function, neurogenesis, cell death, and other processes linked to epileptogenesis. The aim of this ...