BACKGROUND Some national guidelines recommend the use of water alone for napkin cleansing. Yet, there is a readiness, amongst many parents, to use baby wipes. Evidence from randomised controlled trials, of the effect of baby wipes on newborn skin integrity is lacking. We conducted a study to examine the hypothesis that the use of a specifically formulated cleansing wipe on the napkin area of ne...

Throughout the world, large numbers of manual workers perform physically demanding labour in conditions of high environmental heat stress. Although the importance of adequate hydration in combating heat stress is universally recognized, studies in a range of worker groups have demonstrated a disturbingly poor hydration level in a high proportion of at-risk workers. Management of work in hot env...

Preterm birth is a major global health problem that results in a large number of infant deaths, many of which are attributable to the complications of an immature epidermal permeability barrier (EPB), for which there is currently no effective therapeutic option. The mammalian EPB is formed during development and is essential for survival as it maintains thermoregulation and hydration, and provi...

In this study, we evaluated the effect of Lactobacillus plantarum HY7714 on skin hydration in human dermal fibroblasts and in hairless mice. In Hs68 cells, L. plantarum HY7714 not only increased the serine palmitoyltransferase (SPT) mRNA level, but also decreased the ceramidase mRNA level. In order to confirm the hydrating effects of L. plantarum HY7714 in vivo, we orally administered vehicle o...

Psoriasis. Due to primary genetic defects, the epidermal permeability barrier is vulnerable in psoriatic subjects. Mechanical traumas, such as scratches or abrasion, damage the skin barrier, especially during low humidity seasons, such as the winter. While barrier function can be readily maintained in normal subjects, in psoriatic patients, a compromised barrier cannot be completely repaired po...

background: pancreatitis is a serious complication of endoscopic retrograde cholangiopancreatography (ercp) and may cause significant morbidity and even death. there is no effective prophylactic intervention for patients with average risk yet. this study aims to investigate preventive effect of aggressive hydration for post-ercp pancreatitis. materials and methods: in a double-blind controlled ...

A significant increase in the severity of clinical manifestations various dermatoses accompanied by dry skin often increases feeling discomfort and itching skin, significantly reducing patient's quality life. This leads to search for effective ways correct dryness maintain proper functioning epidermal barrier dermatoses. The aim study was effect using a combined emollient, which includes compon...