نتایج جستجو برای: epc

تعداد نتایج: 9068  

Journal: :American journal of physiology. Renal physiology 2007
Peter E Westerweel Imo E Hoefer Peter J Blankestijn Petra de Bree Dafna Groeneveld Olivia van Oostrom Branko Braam Hein A Koomans Marianne C Verhaar

Patients with end-stage renal disease (ESRD) on hemodialysis have an increased risk of cardiovascular disease (CVD). Circulating endothelial progenitor cells (EPC) contribute to vascular regeneration and repair, thereby protecting against CVD. However, circulating smooth muscle progenitor cells (SPC) may contribute to adverse vascular remodeling. We hypothesized that an imbalance occurs between...

2017
Junhao Huang Shen Wang Fengpeng Xu Dan Wang Honggang Yin Qinhao Lai Jingwen Liao Xiaohui Hou Min Hu

OBJECTIVE Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently, irisin has been reported to have a critical role in the regulation of EPCs. This exercise-induced myokine has been demonstrated ...

2017
Cody T Haun Michael D Roberts Matthew A Romero Shelby C Osburn Christopher B Mobley Richard G Anderson Michael D Goodlett David D Pascoe Jeffrey S Martin

PURPOSE We sought to compare the effects of external pneumatic compression (EPC) and sham when used concurrently with resistance training on performance-related outcomes and molecular measures related to recovery. METHODS Twenty (N = 20) resistance-trained male participants (aged 21.6±2.4 years) were randomized to balanced sham or EPC intervention groups. The protocol consisted of 3 consecuti...

Journal: :European heart journal 2010
Mario Gössl Ulrike I Mödder Rajiv Gulati Charanjit S Rihal Abhiram Prasad Darrell Loeffler Lilach O Lerman Sundeep Khosla Amir Lerman

AIMS Endothelial progenitor cells (EPC) may participate in the repair of injured coronary endothelium. We have recently identified EPC co-expressing the osteoblastic marker osteocalcin [OCN (+) EPC] and found that their numbers are increased in patients with early and late coronary atherosclerosis. The current study was designed to test the hypothesis that early coronary atherosclerosis is asso...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2003
Jacob George Itzhak Herz Emil Goldstein Soulico Abashidze Varda Deutch Ariel Finkelstein Yoav Michowitz Hylton Miller Gad Keren

OBJECTIVE Intact endothelialization machinery is essential to facilitate vessel healing after stent placement and to prevent restenosis. Circulating endothelial progenitor cells (EPC) have been demonstrated in the peripheral blood and shown to display endothelial functional properties, along with the ability to traffic to damaged vasculature. We reasoned that robust in-stent intimal growth coul...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2004
Jin-Ho Choi Koung Li Kim Wooseong Huh Beom Kim Jonghoe Byun Wonhee Suh Jidong Sung Eun-Seok Jeon Ha-Young Oh Duk-Kyung Kim

OBJECTIVE Increased risk of cardiovascular disease in patients with chronic renal failure (CRF) has been explained by accelerated atherosclerosis and impaired angiogenesis, in which endothelial progenitor cells (EPCs) may play key roles. We hypothesized that altered EPC biology may contribute to the pathophysiology of CRF. METHODS AND RESULTS EPCs were isolated from CRF patients on maintenanc...

Journal: :Human nature 2008
Paul W Andrews Steven W Gangestad Geoffrey F Miller Martie G Haselton Randy Thornhill Michael C Neale

Despite the importance of extrapair copulation (EPC) in human evolution, almost nothing is known about the design features of EPC detection mechanisms. We tested for sex differences in EPC inference-making mechanisms in a sample of 203 young couples. Men made more accurate inferences (φmen = 0.66, φwomen = 0.46), and the ratio of positive errors to negative errors was higher for men than for wo...

2014
Jacob George Marco Matucci-Cerinic Iris Bar Sara Shimoni

OBJECTIVE Endothelial progenitor cells (EPC) are committed to transform into EC promoting vasculogenic ischemic repair. Anti-endothelial cells (AECA) have been described in various disorders with an associated vascular damage. Herein, we explored a novel circulating population of IgG reactive with EPC, in patients with differential risk profile for atherosclerotic vascular disease. APPROACH A...

2013
Peter E. Westerweel Martin Teraa Shahin Rafii Janneke E. Jaspers Ian A. White Andrea T. Hooper Pieter A. Doevendans Marianne C. Verhaar

BACKGROUND Circulating Endothelial Progenitor Cell (EPC) levels are reduced in diabetes mellitus. This may be a consequence of impaired mobilization of EPC from the bone marrow. We hypothesized that under diabetic conditions, mobilization of EPC from the bone marrow to the circulation is impaired -at least partly- due to dysfunction of the bone marrow stromal compartment. METHODS Diabetes was...

2009
Michael Morley Lockard

Title of Document: THE EFFECT OF THROMBIN ON ENDOTHELIAL PROGENITOR CELLS WITH EXERCISE AND EXERCISE TRAINING. Michael Morley Lockard, Ph.D., 2009 Directed By: Professor James Hagberg, Ph.D. Department of Kinesiology BACKGROUND: Circulating number of endothelial progenitor cells (EPCs) and EPC colony forming units (EPC-CFUs) have emerged as valuable predictors of cardiovascular health. Improvem...

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