The present study was designed to evaluate the biological potentials and phenolic composition of different parts Glaucosciadium cordifolium, which is less investigated known as a wild endemic species Turkey. antioxidant activity plant determined using 2,2-diphenyl-1-picrylhydrazyl (DPPH), 2,2'-Azinobis-(3-Ethylbenzthiazolin-6-Sulfonic Acid) (ABTS), iron chelating capacity, ?-carotene / linoleic...

About 100 million people worldwide have type II diabetes (T2D), making it one of the most common metabolic diseases. DPP-IV (dipeptidyl peptidase-IV) inhibitors are new class anti-diabetic drugs. Gold complexes known for diverse biological activities. Considering these precedents, and growing interest in developing metal-based enzyme inhibitors, we report here inhibitory potential cationic, neu...

Abstract: Aim/ Background: Pancreatic lipase (PL) inhibition has been suggested to be an effective method for obesity management. In this study, 10 novel thiazole-benzimidazole conjugates were designed. Materials and Methods: Conjugates initially screened via in silico experiments, such as ADMET analysis molecular docking, identify the most promising PL inhibitors. Results: Results revealed tha...

objective(s): in food industry, the inhibition of tyrosinase is very important, because this enzyme catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones, which contribute in undesirable color and taste of fruits and vegetables. teucrium polium l. var. gnaphalodes (lamiaceae), a wild-growing flowering plant that has many applications in food preparations and...

Inhibition of the mammalian soluble epoxide hydrolase (sEH) is a promising new therapy in the treatment of disorders resulting from hypertension and vascular inflammation. A spectrophotometric assay (4-nitrophenyl-trans-2,3-epoxy-3-phenylpropyl carbonate, NEPC) is currently used to screen libraries of chemicals; however this assay lacks the required sensitivity to differentiate the most potent ...

Abstract Silver/silver chloride (Ag/AgCl) is ubiquitous in the field of electrochemical biosensing due to its suitability as a reference electrode material. However, we recently discovered that screen-printed Ag/AgCl ink has detrimental effect on Alcohol Oxidase enzyme stability. We performed an optical absorbance assay isolate interaction and discover surprisingly strong inhibition effect. The...

Monoclonal antibodies were derived against the SA11 simian, NIC bovine, and Wa human rotavirus strains and characterized by enzyme-linked immunosorbent assay, plaque neutralization, and hemagglutination inhibition. Several strain SA11-specific antibodies were found to have neutralizing and hemagglutination-inhibiting capacity.

A rapid, high-sensitivity, chemiluminescence (CL) enzyme assay for the determination of organophosphate (OP) residues in milk is presented. The assay for quantification of OP residues in milk is based on the inhibition of enzyme butyrylcholinesterase (BuChE). BuChE was stabilized and preloaded in 384 well plates at 30 °C. The assay permits rapid determination of OPs in milk within 12 min includ...