+*Jennings, L M; *Galvin, A L; *Fisher J +Institute of Medical & Biological Engineering, Leeds, UK [email protected] Introduction There is increasing interest in the coupling of highly cross-linked polyethylene with large diameter heads in the hip, due to the reported lower wear characteristics of highly cross-linked polyethylene compared to conventional polyethylene [1, 2, 3]. Further, ...

Engineering ceramics have high stiffness, excellent thermostability, and relatively low density, but their brittleness impedes their use as structural materials. Incorporating carbon nanotubes (CNTs) into a brittle ceramic might be expected to provide CNT/ceramic composites with both high toughness and high temperature stability. Until now, however, materials fabrication difficulties have limit...

The main principle of a bone tissue engineering (BTE) strategy is to cultivate osteogenic cells in an osteoconductive porous scaffold. Ceramic implants for osteogenesis are based mainly on hydroxyapatite (HA), since this is the inorganic component of bone. Rapid Prototyping (RP) is a new technology in research for producing ceramic scaffolds. This technology is particularly suitable for the fab...

The purpose of this study was to evaluate the bioactivity and cell response of a well-characterized Nurse's A-phase (7CaO·P₂O₅·2SiO₂) ceramic and its effect compared to a control (tissue culture polystyrene-TCPS) on the adhesion, viability, proliferation, and osteogenic differentiation of ahMSCs in vitro. Cell proliferation (Alamar Blue Assay), Alizarin Red-S (AR-s) staining, alkaline phosphata...

In this work, we investigated whether osteo-inductive constructs can be generated by isolationand expansion of sheep bone marrow stromal cells(BMSC) directly within three-dimensional (3D) ceramicscaffolds, bypassing the typical phase of monolayer (2D)expansion prior to scaffold loading. Nucleated cells fromsheep bonemarrowaspiratewere seeded into 3D ceramicscaffolds ...

This paper presents a stress analysis of the ceramic femoral heads of hip joint prostheses with different borehole shapes to evaluate their mechanical reliability in terms of stress concentration. Under the ideal loading conditions used for ceramic rupture tests specified by the ISO 7206-5 standard, a finite element (FE) modeling is performed to determine the tensile and hoop stress distributio...

In situ imaging and strain determination during fracture in a SiC/SiC ceramic matrix composite J. Ramirez-Rico,a,b,⇑ F. Stolzenburg, J.D. Almer, J.L. Routbort, D. Singh and K.T. Faber Department of Materials Science and Engineering, Northwestern University, Evanston, IL 60208, USA Dpto. Fı́sica de la Materia Condensada – ICMS, Universidad de Sevilla – CSIC, 41012 Sevilla, Spain Argonne National ...