The fuel cell (FC) is a new technology for large-scale power generation. Providing of fast and sufficient air concentration in the FC cathode key to prevent oxygen starvation extend life cycle FC. proton exchange membrane (PEMFC) parameter variations output current disturbances can significantly influence on airflow subsystem performance. For this purpose, paper addresses robust control synthes...

Stationary-phase Escherichia coli cultures showed enhanced osmotic resistance as compared with cultures in mid-logarithmic growth or preadapted to osmotic stress. The osmotolerance that developed during starvation or osmotic adaptation required de novo protein synthesis. Of the 22 polypeptides induced during osmotic shock, five were also starvation proteins.

Extended periods of waking result in physiological impairments in humans, rats, and flies. Sleep homeostasis, the increase in sleep observed following sleep loss, is believed to counter the negative effects of prolonged waking by restoring vital biological processes that are degraded during sleep deprivation. Sleep homeostasis, as with other behaviors, is influenced by both genes and environmen...

Nutrient deprivation can lead to dramatic changes in feeding behavior, including acceptance of foods that are normally rejected. In flies, this behavioral shift depends in part on reciprocal sensitization and desensitization of sweet and bitter taste, respectively. However, the mechanisms for bitter taste modulation remain unclear. Here, we identify a set of octopaminergic/tyraminergic neurons,...

Bacterial growth is often limited by availability of nutrients. Soil, water, and even host environments such as macrophages can be nutrient poor, lacking essential building blocks for growth, including carbon, nitrogen, and phosphorus. The ratios of these elements differ according to the local ecology, so each one of them is limiting in different environments (4, 28). When presented with any ty...

Elite athletes and coaches are in a constant search for training methods and nutritional strategies to support training and recovery efforts that may ultimately maximize athletes' performance. Recently, there has been a re-emerging interest in the role of ketone bodies in exercise metabolism, with considerable media speculation about ketone body supplements being routinely used by professional ...

In skeletal muscle, excitation may cause loss of K+, increased extracellular K+ ([K+]o), intracellular Na+ ([Na+]i), and depolarization. Since these events interfere with excitability, the processes of excitation can be self-limiting. During work, therefore, the impending loss of excitability has to be counterbalanced by prompt restoration of Na+-K+ gradients. Since this is the major function o...

Ketosis, the metabolic response to energy crisis, is a mechanism to sustain life by altering oxidative fuel selection. Often overlooked for its metabolic potential, ketosis is poorly understood outside of starvation or diabetic crisis. Thus, we studied the biochemical advantages of ketosis in humans using a ketone ester-based form of nutrition without the unwanted milieu of endogenous ketone bo...

Endogenous energy stores are continuously oxidized for fuel . Triglyceride present in adipose tissue is the major fuel reserve in the body and is critical for survival during periods of starvation (Table 15-1) . The high energy density and hydrophobic nature of triglycerides make it a fivefold better fuel per unit mass than glycogen . Triglycerides liberate 9 .3 kcal/g when oxidized and are com...

The pyruvate dehydrogenase complex (PDC) has a pivotal role in islet metabolism. The pyruvate dehydrogenase kinases (PDK1–4) regulate glucose oxidation through inhibitory phosphorylation of PDC. Starvation increases islet PDK activity (Am J Physiol Endocrinol Metab 270:E988–E994, 1996). In this study, using antibodies against PDK1, PDK2, and PDK4 (no sufficiently specific antibodies are as yet ...