GENERAL INFORMATION Key points: (a) Polycystic kidney disease (PKD) is one of the most common genetic disorders; (b) There are two main types of PKD – autosomal dominant (most common) and autosomal recessive; (c) Diagnosis of PKD relies on a combination of clinical history, family history, imaging studies (computed tomography, ultrasound) and clinical findings (hematuria, hypertension, proteinu...

Erectile dysfunction is more common than realised and can be the first indication of systemic disease. Penile prosthesis a low-risk intervention with high patient satisfaction, previously deemed an endstage form management. However, improvements in devices recent American Association Urology recommendation could change that.

Dietary management, in particular salt and protein restriction is fundamental for the proper care of CKD patients. Therefore, a practical guide to the dietary treatment may be helpful among progressive CKD patients. In Japan, two academic societies such as Japanese Society of Nephrology and Japanese Society for Dialysis Therapy have recently published Guidelines for Dietary Management for non-d...

A 49-year-old Hispanic female was admitted to the hospital with sepsis and an infected upper extremity arteriovenous fistula dialysis port. Her medical history was significant for dialysis-dependent, endstage renal disease for the previous six years. Additional history was limited due to language barriers but included hypertension and hyperlipidemia. Blood cultures from admission grew Staphyloc...

The World Health Organization (WHO) has underscored unipolar depressive disorders as one of the leading causes of total disability-adjusted life-years (DALYs) worldwide [1]. Depression in combination with a medical or psychiatric illness; also known as ‘compound depression’ is of higher intensity and more difficult to manage than unipolar depression [2-4]. In patients with endstage renal diseas...

Amyotrophic lateral sclerosis is a progressive neurodegenerative disease that targets some somatic motoneuron populations, while others, e.g. those of the oculomotor system, are spared. The pathophysiological basis of this pattern of differential vulnerability, which is preserved in a transgenic mouse model of amyotrophic lateral sclerosis (SOD1(G93A)), and the mechanism of neurodegeneration in...

IntroductionPhysical inactivity is most prevalent in hemodialysis population and associated with a variety of unfavourable clinical outcomes. Fatigue elevated biochemical markers are directly linked to decreased physical activity. Intradialytic exercise one the non-pharmacological interventions for end-stage renal disease (ESRD) patients receiving which seldom implemented at centers. This pilot...

Diabetic nephropathy is the number one cause of endstage renal disease in the United States. Blood pressure is most important in delaying the progression of renal disease in persons with diabetes and, agents that block the renin angiotensin system (RAS) should be the primary agents used to achieve blood pressure reduction. There is debate regarding which method of RAS blockade should be used as...

Background: Endstage renal disease (ESRD) is increasingly being recognized as a major public health issue globally. Planning of intervention measures is preferably hinged on what is known about outcome parameters. Objectives: This study investigated the influence of anxiety with depression and psychosocialand treatment-related correlates on quality of life (QOL) in ESRD. Methodology: Overall, 1...