Male and female albino rats given different oral doses (0.75, 2.5, 5.0 and 0.25, 0.75, 1.5 mg/kg/D) of endosulfan respectively for a period of 30 days elicited signs of toxicity such as hyperexcitability, tremor, dyspnea and salivation for a brief period. At the tested dose levels, endosulfan produced no significant change in the organ body weight ratio, biochemical, histological, haematologica...

The present experiment was designed to make a systematic study of experimentally induced immunotoxicity of endosulfan and its amelioration with Ocimum sanctum in male Wistar rats at 6, 3 and 1.5 mg / Kg b.wt to groups II, III and IV by mixing in ground nut oil for 6 weeks. To the groups V, VI and VII in addition to endosulfan as above mentioned dose, Ocimum sanctum was given at 200 mg / kg b.wt...

Recently use of endosulfan has aroused a great concern among clinical and basic neuroscientists as besides adult population even the children residing in some areas of touristic state of Kerala, India which are under constant spraying of endosulfan had shown symptoms of CNS dysfunctioning including cerebral palsy, retardation of mental and physical growth, epilepsy and various congenital anomal...

Acute toxicity tests for the pesticides endosulfan and malathion on the larvae of Chironomus ramosus were conducted. Median Lethal Concentration (LC50) values of endosulfan were 0.55 x 10(-2), 0.16 x 10(-2), 0.089 x 10(-2) and 0.036 x 10(-2) ppb respectively, while those for malathion were 0.139 x 10(-2), 0.054 x 10(-2), 0.019 x 10(-2) and 0.0032 x 10(-2) ppb respectively, at 24, 48, 72 and 96 ...

Endosulfan, an organochlorine (OC) insecticide belonging to the cyclodiene group, is one of the most commonly used pesticides to control pests in vegetables, cotton and fruits. To evaluate the health risk due to the exposure to Endosulfan in the environment, a framework was developed by combining three sub – models: (1) the fugacity model which evaluates the dynamic performance of Endosulfan in...

Endosulfan is a pesticide of organochlorine group. The lipophilic nature of endosulfan suggests that endosulfan initially accumulates in fatty tissues and that relatively high amounts can be found in the liver and kidneys after exposure. In the present investigation spermatozoa architecture after endosulfan treatment in mice have been evaluated. Hence, the dose of 3 mg/Kg b.w of Endosulfan was ...

Endosulfan has emerged as a major environmental menace worldwide due to  extensive usage and environmental persistence, seeking its remedial by a cheaper and efficient means. Therefore, natural resource (soil) was explored to search a potential candidate for biodegradation of endosulfan. A soil bacterium was enriched and isolated by applying a strong nutritional selection pressure, using a non-...

The objective of this study was to find and validate estrogen-related biomarkers from plasma proteins in Oryzias latipes after exposure to an estrogen disrupting compound, α-endosulfan. The acute toxicity of α-endosulfan on O. latipes after 96 h of exposure was 13.72, 16.18, and 22.18 μg L(-1) for the LC10, LC20, and LC50 values, respectively. To confirm estrogenic disturbance by α-endosulfan, ...

The effects of two different categories of pesticides viz. chlorpyrifos (an organophosphate) and endosulfan (an organochlorine cyclodiene) were evaluated on soil dehydrogenase activity. The medium and higher dose of endosulfan resulted in the significant decrease in dehydrogenase activity till third and fourth week of treatment, respectively. In case of chlorpyrifos, decrease in dehydrogenase a...