BACKGROUND Endometriosis is a prevalent gynecologic disease associated with systemic chronic inflammation, heightened oxidative stress, and atherogenic lipid profile that may increase women's risk for coronary heart disease (CHD). METHODS AND RESULTS We examined the prospective association between laparoscopically confirmed endometriosis and subsequent CHD among 116 430 women in the Nurses' H...

INTRODUCTION Endometriosis is defined as overgrowth of endometrial tissue outside the uterine cavity. Endometriosis may be asymptomatic or associated with dysmenorrheal symptoms, dyspareunia, pelvic pain, abnormal uterine bleeding and infertility. The aim of this study was to explore the risk factors related to endometriosis among infertile Iranian women. MATERIAL AND METHODS In this case con...

BACKGROUND Initial publications examining the hereditary aspects of endometriosis appeared in the early seventies and demonstrated an up to seven-fold risk for endometriosis in first-degree relatives of endometriosis patients. The aim was to evaluate the influence of hereditary aspects on the endometriosis risk in our patient collective. METHODS In a retrospective cohort study we evaluated th...

STUDY QUESTION To what extent do the management of endometriosis and the symptoms that remain after treatment affect the quality of life in women with the disease? SUMMARY ANSWER Many women with endometriosis had impaired quality of life and continued to suffer from endometriosis-associated symptoms even though their endometriosis has been managed in tertiary care centres. WHAT IS KNOWN ALR...

Objective: Pain is one of the most important outcomes in RA. Therefore, as objective as possible assessment of pain is necessary for reliable clinical evaluation and effective treatment planning. The purpose of the present study was to evaluate three pain measures in the sample of 151 newly-diagnosed RA-patients. More specifically, this study evaluates the construct validity of pain instruments...

BACKGROUND In four randomized, controlled, European trials, dienogest 2 mg once daily demonstrated significant efficacy for lesion reduction and reduction in pain intensity in endometriosis. We describe a pooled analysis of the safety and tolerability data from these trials to confirm and further characterize the safety profile of dienogest in the treatment of endometriosis. METHODS All 332 w...

We examined whether narratives related to mental health and pain in 120 women with endometriosis. Participants wrote about endometriosis, rated the on centrality identity positive negative self-change, completed measures of depressive symptoms, life-satisfaction, intensity symptoms. Narratives were content-coded for themes agency communion. Higher identity, more lower communion poorer health. w...

INTRODUCTION The present study aimed to investigate clinical, lifestyle, and environmental factors associated with endometrioma (OMA) and/or deep infiltrating endometriosis (DIE) as determined by case-control comparison [women with superficial peritoneal endometriosis (SUP) or no endometriosis], and compare differences between factor associated with endometriosis at a national level. METHODS ...