endometrial stromal sarcomas (ess) are the second most common uterine sarcomas. endometrial stromal sarcomas account for 0.25% of all uterine malignancies. uterine sarcomas most often affect postmenopausal women. the aim of this retrospective study was to review the experience in the treatment and clinical outcome of low grade malignant endometrial stromal sarcoma. seventeen patients with histo...

We report a case of double uterine tumor resembling ovarian sex cord tumor (UTROSCT). The tumor was composed of sex cord-like cords, nests and tubules, and bundles of myoid cells. The lesion was interesting especially in regard to histogenesis of intratumoral myoid cells. It is not known whether these cells are neoplastic or whether they represent preexisting myometrial smooth muscle cells entr...

Hyperplasia of the endometrial stroma is a poorly recognized lesion, lacking widespread recognition with most, if not all, such cases sequestrated in the literature as endometrial stromal nodules or low-grade endometrial stromal sarcomas. In this paper, we describe three examples of "endometrial stromal hyperplasia" which have a remarkable morphological similarity with the normally proliferatin...

background: endometriosis is the presence of endometrial tissue outside of the uterine cavity and is the most common gynecologic disorder in women of reproductive age. we have preliminary evidence that in the presence of a 3-dimensional (3-d) fibrin matrix, human endometrial glands, stroma, and neovascularization can develop in vitro, mimicking the earliest stages of endometriosis. the aim of t...

We have investigated the possible roles of oncostatin M (OSM), which is a member of the interleukin-6 family of cytokines, in endometrial and endometriotic stromal cell growth. Endometrial and endometriotic stromal cells were collected from the uterus or ovarian chocolate cysts. We observed the expression of mRNA transcripts for OSM, OSM receptor subunit beta, leukaemia inhibitory factor recept...

background: repeated implantation failure (rif) is one of the most intricate obstacles in assisted reproduction. the cytokine and chemokine composition of uterine cavity seem to play important roles in the implantation process. objective: to compare the cytokine profile in the endometrium of normal fertile women and those with repeated implantation failure. methods: after enzymatic digestion of...

gastrointestinal stromal tumors (gist) are the most common mesenchy­mal tumors of the gastrointestinal tract. the biological pattern of these tumors ranges from benign-appearing small lesions to malignant sarcomas. only 3%-5% of gists are found in the duodenum. a duodenal gist is a rare source of upper gastrointestinal bleeding. a remarkable percentage of duodenal gists are localized in the thi...

Endometrial stromal sarcomas are rare uterine malignancies with a high capacity for recurrence, even in cases diagnosed at an early stage of the disease. Recurrence is usually confined to the pelvic space but sometimes accelerated growth and extension into the upper abdomen can be found. In such cases, an aggressive surgical approach might be needed in order to provide complete resection of the...

Introduction and Aim: Stromal malignancies of uterus are rare accounts for 1-3% all female genital tract malignancies. They known to pose a diagnostic challenge the clinicians pathologists. show non-specific clinical features, gross appearance, varying histological immunohistochemical features. This study highlights important clinical, morphologic features these tumors. Methodology: Histopathol...