نتایج جستجو برای: endocrine disrupting chemicals

تعداد نتایج: 97981  

2016
Yukun Liu Yayun Yao Huan Li Fang Qiao Junlin Wu Zhen-yu Du Meiling Zhang

Gender is one of the factors influencing the intestinal microbial composition in mammals, but whether fish also have gender-specific intestinal microbial patterns remains unknown. In this decade, endocrine disrupting chemicals in surface and ground water of many areas and increasing observation of freshwater male fish displaying female sexual characteristics have been reported. Here we identifi...

Journal: :Reproductive biomedicine online 2013
Jure Knez

Endocrine-disrupting chemicals are substances present in the environment that can interfere with normal hormonal balance and thus exert potentially adverse health effects on the human organism. Male reproductive system development and function may be susceptible to the effects of such environmental toxicants. Bisphenol A, phthalates and alkylphenols are important components of multiple products...

Journal: :Environmental Health Perspectives 1997
J Ashby E Houthoff S J Kennedy J Stevens R Bars F W Jekat P Campbell J Van Miller F M Carpanini G L Randall

Rapid regulatory developments in the area of environmental endocrine disruption present a series of potential problems that are identified and illustrated with examples taken from the recent literature. A list of priorities is provided, including the need for additional epidemiological and wildlife studies, the derivation of a coordinated testing strategy, agreement on the toxicities expected o...

Journal: :The Journal of steroid biochemistry and molecular biology 2011
Thaddeus T Schug Amanda Janesick Bruce Blumberg Jerrold J Heindel

Environmental chemicals have significant impacts on biological systems. Chemical exposures during early stages of development can disrupt normal patterns of development and thus dramatically alter disease susceptibility later in life. Endocrine disrupting chemicals (EDCs) interfere with the body's endocrine system and produce adverse developmental, reproductive, neurological, cardiovascular, me...

1999
Stephan Lutter

At the same time harbour porpoises, that had died of a similar virus, appeared stranded on the beaches. Two years later another mass die-off occurred in the Mediterranean striped dolphin populations. The severe and lethal outcomes of the epidemics led many in the scientific community to believe that a contaminantinduced immune deficiency was responsible for the high mortality during the epidemi...

Journal: :Pediatrics 2008
Germaine M Buck Louis L Earl Gray Michele Marcus Sergio R Ojeda Ora H Pescovitz Selma Feldman Witchel Wolfgang Sippell David H Abbott Ana Soto Rochelle W Tyl Jean-Pierre Bourguignon Niels E Skakkebaek Shanna H Swan Mari S Golub Martin Wabitsch Jorma Toppari Susan Y Euling

Serono Symposia International convened an expert panel to review the impact of environmental influences on the regulation of pubertal onset and progression while identifying critical data gaps and future research priorities. An expert panel reviewed the literature on endocrine-disrupting chemicals, body size, and puberty. The panel concluded that available experimental animal and human data sup...

2009
Peter Lin Sun Shinn-Shoung Tsai

River pollution in Taiwan is rather serious, but so far there have been no reports of fish intersex problems. This report reveals that 50% male tilapia in the Era-Jiin River of southern Taiwan were found to be feminized in an October 8, 1994 collection from station EJ-2 of this river. After discounting all other possible causative factors, and correlating with endocrine disrupting chemicals fou...

2015
Laura Gioiosa Paola Palanza Stefano Parmigiani Frederick S. vom Saal

We review here our studies on early exposure to low doses of the estrogenic endocrine-disrupting chemical bisphenol A (BPA) on behavior and metabolism in CD-1 mice. Mice were exposed in utero from gestation day (GD) 11 to delivery (prenatal exposure) or via maternal milk from birth to postnatal day 7 (postnatal exposure) to 10 mg/kg body weight/d of BPA or no BPA (controls). Bisphenol A exposur...

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