In this paper we introduce a new spatio-temporal methodology for biosurveillance entitled the Repeated Two-sample Rank (RTR) procedure. It is designed to sequentially incorporate information from individual observations and thus can operate on data in real-time as it arrives into an automated biosurveillance system. In addition, upon a signal of a possible outbreak, the methodology suggests a w...

BACKGROUND CMV disease remains a major complication of lung transplantation and attempts to prevent it have met with marginal success. In a previous study we documented that universal prophylaxis did not prevent CMV disease but merely delayed it, and was very costly. METHODS We compared the efficacy and cost of pre-emptive therapy with ganciclovir, guided by CMV antigenemia, to that of histor...

background: according to previous studies there are some different opinions on the pre-emptive effects of paracetamol in controlling post-operative pain, we aimed to compare the analgesic effects of pre-emptive paracetamol with post-operative paracetamol and morphine in patients undergoing septorhinoplasty. materials and methods: a hundred and six patients aged 15 to 50 were divided into 3 grou...

onsi al-haj tended surrealism in the beginning of his poetic life. his surrealistic poems have been told according to the unconsciousness and automatic writing .  so his poems are written with a unconscious style of writing. trusting on unconsciousness by onsi al-haj has influenced on his poems in some aspects. one of these aspects is his language; al-haj's language is an ambiguous languag...

Pre-emptive kidney transplantation is considered the best available renal replacement therapy, but no guidelines exist to direct its timing during CKD progression. We used a national cohort of 19,471 first-time pre-emptive kidney transplant recipients between 1995-2009 to evaluate patterns and implications of transplant timing. Mean estimated GFR (eGFR) at the time of pre-emptive transplant inc...