For purposes of this short communication, sonographic (ultrasound) techniques that utilize microbubbles (MB) is referred to as microbubble sonography (MBS). MBS has important diagnostic and therapeutic (thus the term "theranostic") clinical applications in targeted or “personalized” oncology. For diagnosis, MBS provides detailed depiction of tumor microvascularity and a means to monitor its res...

A filterbank-based algorithm for time-varying spectral analysis is proposed. The algorithm, which is an enhanced realization of the conventional spectrogram, consists of hundreds or thousands of highly overlapping wideband filter/detector stages, followed by a peak detector that probes the filter/detector outputs at very short time intervals. Analysis with synthetic modulated signals illustrate...