Direct evidence that IGF-I has any significant effect on embryo growth is lacking. We therefore studied the effect of administration of IGF-I on the chick embryo in ovo. Five hundred ng pure IGF-I (purified from human plasma) were given to chick embryos on 2 occasions (7 and 14 d) by injection directly into the allantoic sac. Treated and control (saline injected) chicks hatched on the same day ...

Objective: Rice Bran Oil (RBO) is extracted from the outer layer of rice. Little information is available regarding its safety. The present study was conducted to assess its safety in chicken embryo model. Materials and Methods: RBO was injected on day 4 of incubation of chickens. The tissues and serum samples were collected. Oxidative stress parameters in the liver, kidney and brain and bioche...

The production of red blood cells, termed erythropoiesis, occurs in two waves in the developing mouse embryo: first primitive erythropoiesis followed by definitive erythropoiesis. In the mouse embryo, both primitive and definitive erythropoiesis originates in the extra-embryonic yolk sac. The definitive wave then migrates to the fetal liver, fetal spleen and fetal bone marrow as these organs fo...

Transdifferentiation is the name used to describe the direct conversion of one differentiated cell type into another. Cells which have the potential to interconvert by transdifferentiation generally arise from adjacent regions in the developing embryo. For example, the liver and pancreas arise from the same region of the endoderm. The transdifferentiation of pancreas to liver (and vice versa) h...

PLATES 59 AND 60. While working with a chick embryo of nineteen days' incubation, my attention was attracted by the brilliant yellow color of the liver. The color was like that o f the adrenal cortex, or the corpus luteum, and this resemblance impelled me to investigate more closely the condition of the liver cells. A small fragment of the liver was teased and examined between the Nicol prisms ...

The liver of the embryo chick during the first two weeks of development contains an abundance of isotropic fatty globules which represent a mixture of lipoids in which phosphorized fats predominate. During the third week of incubation the fatty globules in the liver change their physical and chemical characters. They become anisotropic and exhibit the reactions and properties of esters of chole...

 Background & Objective:  Toxico-pathological effects of herbal plants have always been a major concern, but little information is provided on the toxico-pathological effects of origanum on the fetus. Due to ethical rules and regulations, no drug experiment on the human fetus is permitted; hence, the chick embryo model is used as an ideal opportunity to study the adverse effects of drugs. This ...

Background & Aims: Various antiviral drugs such as amantadine are used to treat influenza. This drug is categorized in group C and few researches have been conducted about its toxic effects on human fetus. In the current study, the pathologic effects of the drug as well as drug efficacy in reducing influenza virus titer in the developing chicken embryo were assessed. <br ...

Background The occurrence of hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome before 20 weeks of gestation is rare. HELLP is a possible but rare syndrome in gestational surrogate pregnancies for surrogates with risk factors for development of preeclampsia. Case A 32-year-old patient with chronic hypertension and positive antinuclear antibody presented for prenatal care at 13 we...

Identification of the agent: The virus may be isolated from the liver, spleen and kidneys of birds dying from this infection. Virus may be recovered by infecting susceptible ducklings, in which the disease can be reproduced; by inoculating embryonated Muscovy duck eggs on the chorioallantoic membrane; or by inoculating cell cultures of duck embryo or Muscovy duck embryo origin. The identity of ...