SUMMARY Increasing evidence suggests that patients with L2-HGA have a predisposition to cerebral neoplasms. This may be related to the pathologic accumulation of L2-HG because high amounts of 2-HG have been found in brain neoplasms that have IDH1 mutations. Our experience, on the basis of 11 previously unreported cases of L2-HGA, 3 of which developed cerebral neoplasms during the course of the ...

primary ureteral neoplasms are very rare and its prevalence is less than 1% of all genitourinary neoplasms. we report a symptomatic giant ureteral fibro epithelial polyp in adult women presenting as a bladder mass which was resected ureteroscopically and reported at the first time from iran. cystoscopy is growing use in the treatment of urinary tract lesions cystoscopy can be used in large lesi...

Neoplasm is the cause of a double disease body, i.e. with two faces (Janus disease), which means both presence cancer cells and secondary disorders immune system function caused by them. The second possibility temporary decrease in immunity, e.g. influenza, revealing neoplastic disease. Neoplasms are induced genetic epigenetic factors (Fig. 1), giving different types mono- polyclonal metastases...

Central nervous system (CNS) neoplasms are the second most common childhood malignancy after leukemia and the most common solid organ neoplasm in children. Diagnostic dilemmas with small specimens from CNS neoplasms are often the result of multifactorial etiologies such as frozen or fixation artifact, biopsy size, or lack of knowledge about rare or unfamiliar entities. Since the late 1950s, ult...

One of the confusing aspects of the lymphoid neoplasms concerns the use of the descriptive terms "lymphocytic leukemia" and "lymphoma." Leukemia is used for lymphoid neoplasms presenting with widespread involvement of the bone marrow, usually accompanied by the presence of large numbers of tumor cells in the peripheral blood. Lymphoma, on the other hand, is used to describe proliferations arisi...