Adaptor proteins allow temporal and spatial coordination of signalling. In this study, we show SUMOylation of the adaptor protein TANK and its interacting kinase TANK-binding kinase 1 (TBK1). Modification of TANK by the small ubiquitin-related modifier (SUMO) at the evolutionarily conserved Lys 282 is triggered by the kinase activities of IκB kinase ɛ (IKKɛ) and TBK1. Stimulation of TLR7 leads ...

A conceptually simple method for linac tuning has been tested on the 200 MeV drift-tube linear accelerator at Fermilab. The phase of a beam-induced signal in a stripline detector is measured as tank phase is scanned over approximately 360 degrees. The stripline detector is downstream of the tuned tank. The resulting phase-scan curves have unique signatures that depend upon only a few critical p...

Elimination of tank overfills is a significant problem for the petroleum industry. Since most tank receiving operations are manual, the operators rely heavily on tank level gauges and alarms for overfill prevention. Tracing the historical development of tank gauging and alarm systems provides insight into why independence is so important. This history is interwoven with interpretations, insight...

The novel ultrasonic NDT technique based on application of long range guided waves is proposed for detection of defects in a storage tank floor. The technique needs access only to the outer edge of the tank floor and do not require emptying and cleaning inside of the tank. The technique has been developed on the basis of the Lamb wave transmission tomography. The propagation of the guided waves...

this paper deals with an inspection of defects including corrosion and leakage by acoustic emission (ae) in an oil tank floor. in contrast to intrusive methods such as magnetic flux leakage, eddy current or ultrasonic, there is no need to emptying and entering the tank in ae method in order to inspection. in this research ae investigation and ae source location is presented in detail. the resul...

Many researchers have investigated how to increase the overall efficiency of solar-driven thermal systems. Several key parameters, such as collector efficiency and storage tank characteristics, may impose some constraints on the annual solar fraction (ASF) of such systems. In this paper, the behaviour of integrating the phase change material (PCM) in SDHW systems is modelled and optimized n...

Internal melt ice-on-coil tank with built-in horizontal tubes is a kind of ice tank used widely. Its discharge process is effected greatly by density different between ice and water. The existing models developed for internal melt ice-on-coil tank are concentric cylinder models which are applicable to tank with built-in vertical tube or to case when all water in tank is frozen, but is not appli...

TRAF family member-associated NF-κB activator (TANK) is a scaffold protein that assembles into the interferon (IFN) regulator factor 3 (IRF3)-phosphorylating TANK-binding kinase 1 (TBK1)-(IκB) kinase ε (IKKε) complex, where it is involved in regulating phosphorylation of the IRF3 and IFN production. However, the functions of TANK in encephalomyocarditis virus (EMCV) infection-induced type I IFN...

Analytical and experimental studies conducted at the NASA Langley Research Center for investigating integrated cryogenic propellant tank systems for a Reusable Launch Vehicle are described. The cryogenic tanks are investigated as an integrated tank system. An integrated tank system includes the tank wall, cryogenic insulation, Thermal Protection System (TPS) attachment sub-structure, and TPS. A...

This study assesses the risk to soil and groundwater in the event of a spill of hazardous materials transported in railroad tank cars. Tank cars are designed to be resistant to damage in accidents to reduce the probability of a spill. For safety and economic reasons, the damage-resistant design of tank cars is commensurate with the degree of hazard posed by the product they are intended to tran...