The term "Electrophysiological remodeling" defines the changes of atrial electrophysiologic properties taking place in atrial myocites during atrial fibrillation and/or following periods of sustained atrial fibrillation (AF). Early research was prompted by clinical observations: many patients were seen to get through increasingly frequent and longer paroxisms of AF to persistent AF, until chron...

Invasive electrophysiologic testing and noninvasive testing were compared as methods for identifying patients with Wolff-Parkinson-White syndrome at risk for sudden death. Sixty-seven patients were studied, including nine with a history of ventricular fibrillation. Electrophysiologic testing, using the shortest interval between consecutive pre-excited beats (shortest RR interval) less than or e...

The authors carried out genetic analyses and visual electrophysiologic evaluations in six asymptomatic sons and daughters of patients with symptomatic cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). Three subjects showed Notch3 Cys146Tyr missense mutation and a dysfunction of the outer, middle, and innermost retinal layers, with normal neura...

DURING the past decade, there has been enormous interest in the use of invasive electrophysiologic testing to evaluate patients with cardiac arrhythmias and conduction disturbances. In this editorial, we present our views on the clinical value of this procedure, ever mindful of our own biases and the knowledge that many important issues in this rapidly expanding area of cardiology remain contro...

T HIS STUDY was undertaken to demonstrate the feasibility of use of a computer program to extract automatically, without human intervention, clinically useful measurements of the parameters of an electrophysiologic tracing. The electrocardiogram was selected as the most suitable model of an electrophysiologic signal from which to extract data because of the large backlog of electrocardiographic...

Cardiac arrhythmias are common in chagasic patients. Electrophysiologic study is an invasive procedure for the investigation of sinus node function, atrioventricular node conduction and intraventricular (His-Purkinje) conduction and the mechanism of tachycardias. It is useful in elucidating syncope, dizziness and tachycardiac palpitations that remain unexplained by non-invasive diagnostic metho...

The goal of the present study was to investigate electrophysiologic, qEEG, changes when individuals were exposed to a motor task. Subjects brain electrical activity was analyzed before and after the typewriting training task. For the neurophysiological variable asymmetry, a paired t-test was performed to compare each moment, pre and post-task, in the beta bands. The findings showed a change for...

This case was selected to highlight the importance of the test battery approach in the assessment of a child with auditory processing deficits. The utility of behavioral, electrophysiologic, acoustic immittance, and evoked otoacoustic emission procedures, as well as the problems associated with interpreting these multiple measures with differing results, is discussed. This case was confounded b...

Individuals having frequent abnormal heartbeats interspersed with normal heartbeats may be at an increased risk of sudden cardiac death. However, mechanistic understanding of such cardiac arrhythmias is limited. We present a visual and qualitative method to display statistical properties of abnormal heartbeats. We introduce dynamical "heartprints" which reveal characteristic patterns in long cl...

Electrophysiologic studies were performed in a patient who had an apparently uncomplicated complete trifascicular block. His bundle recordings revealed atrioventricular dissociation with: 1) an atrial rate of 58 beats/min, 2) an idioventricular escape rate of 45 beats/min, and 3) nonparoxysmal junctional tachycardia (His bundle rhythm) at a rate of 65--85 beats/min. The latter arrhythmia was el...