In extremely low birth weight (ELBW) infants, systemic hypotension is associated with poor neurological outcomes as a result of cerebral hypoperfusion. Treatment with arginine vasopressin (AVP) has been shown to increase blood pressure (BP) and urine output in ELBW infants suffering from refractory hypotension. The purpose of this study was to clarify whether low doses of AVP increased renal bl...

OBJECTIVE The Bayley Scales of Infant Development, Second Edition (BSID II) are commonly used to assess outcomes of extremely low birth weight (ELBW) infants. We sought to assess the predictive validity of the BSID II Mental Developmental Index (MDI) for cognitive function at school age. DESIGN/METHODS Of 330 ELBW infants admitted in 1992-1995, 238 (72%) survived to the age of 8 years, of who...

BACKGROUND AND OBJECTIVES Ocular growth and development differs between preterm and term-born infants and may cause long-term negative consequences for visual function, but contemporary data on long-term visual outcomes in representative samples of the highest risk extremely low birth weight (ELBW, <1000 g birth weight) or extremely preterm (EP, <28 weeks' gestation) survivors are lacking. Our ...

Prematurely erupted teeth are rare in fullterm neonates and extremely prematurely delivered infants. The aim of this study was to present macroscopic scanning electron microscopy (SEM) investigations primary preterm very low birthweight (VLBW) (ELBW) Three VLBW ELBW infants with lower incisors were examined. dental examination assessed the type, location, clinical appearance, degree mobility te...

BACKGROUND Currently, there are no nutritional indices to predict cognitive function in extremely low-birth-weight (ELBW) infants. OBJECTIVE To assess the neonatal blood urea nitrogen (BUN) values in ELBW infants according to their cognitive function at the corrected age of 36 months. METHODS This was a retrospective study that assessed the neonatal factors affecting the developmental outco...

INTRODUCTION Infants born extremely preterm (EP; <28 weeks' gestation) and/or with extremely low birth weight (ELBW; <1000 g birth weight) are at increased risk for adverse neurodevelopmental outcomes. However, it is challenging to predict those EP/ELBW infants destined to have long-term neurodevelopmental impairments in order to target early intervention to those in most need. The General Move...

OBJECTIVE Preterm infants are at increased risk of severe rotavirus gastroenteritis. Although immunization with rotavirus vaccine is safe and effective, age restrictions limit the number of infants eligible for vaccination at discharge from the NICU. The objectives of this study were to assess the implementation of the rotavirus vaccine program in our NICU, recognize missed opportunities for va...

CONTEXT Although individual components of neonatal intensive care have proven efficacy, doubts remain about its overall effectiveness. OBJECTIVE To determine the changes in effectiveness of neonatal intensive care for extremely low birth weight (ELBW) infants over 2 decades. DESIGN Population-based cohort study of consecutive ELBW infants born during 4 distinct eras: 1979-1980, 1985-1987, 1...

BACKGROUND We have previously shown that infants who were extremely low birth weight (ELBW) are particularly vulnerable to problems related to inattention and hyperactivity at school age. It is not known whether these problems persist to adolescence. OBJECTIVE To explore and compare the levels of psychopathology in a regional cohort of ELBW infants and sociodemographically matched term contro...

The development of the coagulation and anticoagulation system in preterm infants was assessed, with special emphasis on extremely low birth weight (ELBW) infants and haemorrhagic or other complications after birth. Coagulation factors II (prothrombin), V (FV), VII (FVII) and X (FX) were analysed at birth and at a corrected age of six months. In addition, antithrombin (AT), protein C (PC) and pr...