CB1 and CB2 cannabinoid receptors are the primary targets of endogenous cannabinoids (endocannabinoids). These G protein-coupled receptors play an important role in many processes, including metabolic regulation, craving, pain, anxiety, bone growth, and immune function. Cannabinoid receptors can be engaged directly by agonists or antagonists, or indirectly by manipulating endocannabinoid metabo...

mutannabi the well-known arab poet has dedicated many lines of his poetry to describing animals directly or indirectly. among the animals to whichmutanabbi has paid attention the horse has a very special status. most of the lines in which he has in some way described horses or horse riders are the lines about fights and battles in which the poet depicts the victories and bravery of the courageo...

This article discusses the contribution made by non-viral infections to the global burden of cancer and describes the bacterial, protozoan and fungal organisms that are believed to cause cancer, either directly or indirectly.

In carrying out the activities of daily life humans will always be faced with various possible risks either directly or indirectly. The that occur in can positive (beneficial risk) negative (detrimental risk), hence are encouraged to plan carefully minimize any harm themselves. addition minimizing possibility they also recommended able overcome risk actions called Risk Management.

In a number of important clinical issues such as evaluation of the efficacy or effectiveness of therapeutic or preventive interventions as well as for comparing the harms of interventions, randomized controlled trials (RCTs) provide the highest levels of evidence, either directly or indirectly. It is obvious that critical appraisal of these studies to assess their validity and precision is of p...