totrópica humana. Acta Med Costarric. 2007;49:121–3 [cited 2013 Nov 25]. http://www.scielo.sa.cr/scielo.php?script=sci_ arttext&pid=S0001-60022007000200012&lng=en&nrm=iso 4. Rojas A, Rojas D, Montenegro V, Gutiérrez R, Yasur-Landau D, Baneth G. Vector-borne pathogens in dogs from Costa Rica: first molecular description of Babesia vogeli and Hepatozoon canis infections with a high prevalence of ...

The binding of IL-18 to IL-18Rα induces both proinflammatory and protective functions during infection, depending on the context in which it occurs. IL-18 is highly expressed in the liver of wild-type (WT) C57BL/6 mice following lethal infection with highly virulent Ixodes ovatus ehrlichia (IOE), an obligate intracellular bacterium that causes acute fatal toxic shock-like syndrome. In this stud...

Ehrlichia chaffeensis is an obligately intracellular bacterium that resides and multiplies within cytoplasmic vacuoles of phagocytes. The Ehrlichia-containing vacuole (ECV) does not fuse with lysosomes, an essential condition for Ehrlichia to survive inside phagocytes, but the mechanism of inhibiting the fusion of the phagosome with lysosomes is not clear. Understanding the ECV molecular compos...

BACKGROUND Ehrlichia ewingii, which causes disease in dogs and people, is the most common Ehrlichia spp. infecting dogs in the United States, but little is known about how long E. ewingii infection persists in dogs. HYPOTHESIS/OBJECTIVES To evaluate the persistence of natural infection with E. ewingii in dogs. ANIMALS Four Class A Beagles; no previous exposure to ticks or tick-borne infecti...

Genes located on the two replicating strands are found to have two separate base/codon usages in Ehrlichia canis genome. Although strand-specific codon usage is not the first observation, for the first time we have applied multiple methods to the analysis of strand composition bias. By combining multiple methods, comprehensive and interesting results are obtained. Among three types of correspon...

Blood samples collected from wild deer in Missouri in November of 2000 and 2001 were positive by PCR assays for Ehrlichia chaffeensis (50 of 217; 23%), Ehrlichia ewingii (44 of 217; 20%), and Anaplasma species (214 of 217; 99%). Nucleotide sequences of selected amplicons from the assay for anaplasma matched sequences of the white-tailed deer agent. Serologic analysis of 112 deer sampled in 2000...