OBJECTIVE To evaluate the leishmanicidal activity of saponin, dasyscyphin C of Eclipta prostrata and sapogenin, gymnemagenol from Gymnema sylvestre leaves under in vitro conditions. MATERIALS AND METHODS Dasyscyphin C/Gymnemagenol were dissolved in phosphate buffered saline (PBS) and diluted with liquid medium to obtain concentrations ranging from 1000 to 15 mug /ml. The leishmanicidal activi...

The present study comprises physicochemical and phytochemical evaluation of arial parts of Eclipta alba in different extracts using ethanol, petroleum ether, benzene, chloroform and aqueous solvents by using standard methods. The physical evaluation was carried out for the determination physiochemical profile such as ash values and extractive values, whereas phytochemical evaluation was carried...

Abstract: The present study deals with the leaf extracts of 4 coastal living medicinal plants Viz., Ocimum canum, Acalypha indica, Eclipta alba and Lawsonia inermis for their antibacterial potential. The maximum antibacterial activity was observed with Acalypha indica and Lawsonia inermis against tested pathogens. Proteus mirabilis, Shigella dysenteriae and Staphylococus aureus were found susce...

The non-proliferative activity of isolated saponins, gymnemagenol (C30H50O4) from Gymnema sylvestre and dasyscyphin C (C28H40O8) from Eclipta prostrata leaves were tested under on HepG2 cells under in vitro conditions. Both gymnemagenol and dasyscyphin C exhibited non-proliferative activity on HepG2 cells at 24 h with the IC50 value of 18.5 and 23.5μg/ml respectively. 5Fluorouracil (5FU) a posi...

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