نتایج جستجو برای: ebola haemorrhagic fever
تعداد نتایج: 105351 فیلتر نتایج به سال:
BACKGROUND Nurses are on the forefront and play a key role in global disaster responses. Nevertheless, they are often not prepared for the challenges they are facing and research is scarce regarding the nursing skills required for first responders during a disaster situation. OBJECTIVES To investigate how returnee nursing staff experienced deployment before, during and after having worked for...
BACKGROUND We previously showed that small interfering RNAs (siRNAs) targeting the Zaire Ebola virus (ZEBOV) RNA polymerase L protein formulated in stable nucleic acid-lipid particles (SNALPs) completely protected guineapigs when administered shortly after a lethal ZEBOV challenge. Although rodent models of ZEBOV infection are useful for screening prospective countermeasures, they are frequentl...
Containing a haemorrhagic fever epidemic: the Ebola experience in Uganda (October 2000–January 2001)
The appearance of novel pathogens of humans with epidemic potential and high mortality rates have threatened global health security for centuries. Over the past few decades new zoonotic infectious diseases of humans caused by pathogens arising from animal reservoirs have included West Nile virus, Yellow fever virus, Ebola virus, Nipah virus, Lassa Fever virus, Hanta virus, Dengue fever virus, R...
Several human infections have emerged in the last three decades, most of them are attributed to wildlife origin. Two third emerging zoonotic viruses. Emerging and re-emerging fatal viral diseases like Nipah virus disease, Hendra Virus Severe Acute Respiratory Syndrome, Middle East Ebola Marburg haemorrhagic fever been witnessed recently, causative agents which associated with bats. Ecology bats...
Infections by the Ebola and Marburg filoviruses cause a rapidly fatal haemorrhagic fever in humans for which no approved antivirals are available1. Filovirus entry is mediated by the viral spike glycoprotein (GP), which attaches viral particles to the cell surface, delivers them to endosomes and catalyses fusion between viral and endosomal membranes2. Additional host factors in the endosomal co...
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