We review evidence that the AMIS (Absence of Meal-induced Insulin Sensitization) syndrome describes a paradigm fundamental to development of obesity. The hypoglycemic response to a pulse of insulin is doubled after a meal as a result of Hepatic Insulin Sensitizing Substance (HISS), released from the liver to act selectively on muscle, heart and kidney. In the absence of HISS action, the hypogly...

Desquamation of the gingiva is a sign that may be encountered in clinical practice. Various diseases can affect the gingival tissues. Mild desquamation that is localized may be associated with mechanical irritation or induced by trauma. Moderate to severe generalized desquamation associated with ulceration and erythema may be indicative of a more serious systemic condition. Although often overl...

objective: medically unexplained symptoms are physical symptoms, which cannot be explained by organic ‎causes. this study aimed to investigate mental health in patients with medically unexplained ‎physical symptoms. ‎ method: one hundred outpatients who were admitted to the electro diagnosis clinic of imam khomeini ‎hospital, ahvaz/iran, participated in this study. data were collected using phy...

context worldwide prevalence of respiratory diseases, suffering from such diseases, and heavy cost of treatment, which all may result from lack of etiological understanding of these diseases in modern medicine, were the main factors to conduct the current study. in the present study, the causes and symptoms of asthma were evaluated and compared with those of some other respiratory diseases. ira...

Objective To investigate the gustatory function in patients with semantic dementia (SD). Methods Detection and recognition thresholds of the 4 basic tastes (sweet, salty, sour, and bitter), taste discrimination, and taste identification were evaluated in 18 patients with SD, 18 patients with Alzheimer disease (AD), and 22 healthy controls. Results Total detection and recognition threshold v...

The chronic intermittent hypoxemia which results from sleep apnea causes three effects which quickly elevate the concentration of serum uric acid, often leading to the precipitation of monosodium urate crystals, namely, gout: cell catabolism which culminates irreversibly in the generation of excess uric acid fed into the blood; serum acidosis and hypercapnia which reduces the solubility of uric...

BACKGROUND Singapore is a tropical country with a temperature range of 23 degrees C to 35 degrees C and relative humidity of 48% to 100% throughout the year. Influenza incidence peaks in June through July and November through January, though influenza cases can be detected throughout the year. METHODS Between May 1 and July 28, 2009, a novel dual-gene diagnostic polymerase chain reaction assa...

BACKGROUND Although several risk factors for acute kidney injury (AKI) have been identified, early detection of AKI in acute decompensated heart failure patients remains a challenge. The aim of this study was to develop and validate a risk score for early prediction of AKI in acute decompensated heart failure patients. METHODS AND RESULTS A total of 676 consecutive acute decompensated heart f...

The study is to investigate the importance of early diagnosis and treatment to the prognosis of epilepsy with continuous spikes and waves during slow sleep (CSWS). A total of 8 cases of CSWS children were followed up for 6 months to 4 years. Retrospective analysis of the clinical and electroencephalographic (EEG) characteristics, treatment and prognosis was performed in these 8 cases. Of the 8 ...

BACKGROUND Detection of early stage non-small cell lung cancer (NSCLC) is commonly believed to be incidental. Understanding the reasons that caused initial detection of these patients is important for early diagnosis. However, these reasons are not well studied. METHODS We retrospectively reviewed medical records of patients diagnosed with stage I or II NSCLC between 2000 and 2009 at UT MD An...