Increased awareness of the signs and symptoms of sepsis and an emphasis on the importance of early treatment have helped to improve survival rates from this serious and frequent condition in recent years. With no specific, effective anti-sepsis therapies available, management focuses on early source control with adequate and appropriate antibiotics and removal of any source of infection, rapid ...

Neonatal sepsis (NS) is one of the major causes morbidity and mortality in neonatal age. NS classified according to time symptoms Early-Onset Sepsis (EOS) Late-OnsSepsis (LOS). In new studies, neutrophil/lymphocyte ratio (NLR) platelet/lymphocyte have been used determining existence severity sepsis. This a sign inflammation, it can be foreseeing septicemia.

OBJECTIVE To evaluate serial serum C-reactive protein (CRP) levels for diagnosis of neonatal infection. SETTING A regional intensive care nursery and two community intensive care nurseries. METHODS All neonates treated for suspected bacterial infection were prospectively evaluated using a standardized clinical pathway. Infants were categorized as having proven sepsis (bacteria isolated from...

neonatal sepsis is a disease of infants who are less than 1 month of age. these infants are clinically ill, and their blood culture are positive for bacteria. the reported incidence of neonatal sepsis for allinfants is 1 to 10 per 1000 live births. the mortality rate is 4.2-26%. the clinical signs are not specific and diagnosis of neonatal sepsis is one of the most difficult tasks in clinical m...

Neonatal sepsis is the third leading cause of neonatal mortality and a major public health problem, especially in developing countries. Although recent medical advances have improved neonatal care, many challenges remain in the diagnosis and management of neonatal infections. The diagnosis of neonatal sepsis is complicated by the frequent presence of noninfectious conditions that resemble sepsi...

Background Neonatal sepsis is a critical condition caused by a generalized bacterial infection in the first month of life. The present study aimed to investigate the relationship between serum vitamin D levels and neonatal sepsis. Materials and Methods: A search of online databases (Medl...

Ghrelin, a newly identified endogenous ligand for growth hormone secretagogue receptor 1a (GHSR-1a, i.e., ghrelin receptor), was recently demonstrated to be a potent vasoactive peptide. Although sepsis is characterized by an early, hyperdynamic phase, it remains unknown whether ghrelin or GHSR-1a plays a role in the cardiovascular response to sepsis. To determine this, polymicrobial sepsis was ...

background: neonatal sepsis is a life-threatening disease with an incidence of 1 to 10 per 1000 live births and a mortality rate of 15% to 50%. the clinical signs are non-specific and indistinguishable from those caused by a variety of neonatal noninfectious disorders. objective: the aim of this study was to determine the importance of cd64 expression (fcgri), a neutrophil surface marker, in ea...

Neonatal sepsis is a major cause of morbidities and mortalities mostly remarkable in the third world nations.We aimed to assess the value of simultaneous measurement of procalcitonin (PCT) and interleukin-6 (IL-6) in association with high sensitive prediction of early neonatal sepsis. A follow-up study was performed clinical signs of sepsis or maternal risk factors for sepsis. Neonates were ass...

Introduction:Infections are one of the main causes of death during childhood. According to epidemiological studies in Iran, the incidence of neonatal sepsis was 1.8% in year 1995. Moreover, the incidence of neonatal meningitis was 0.2 to 0.4 in 1000 live births. The aim of this study was to determine the necessity of lumbar puncture (LP) for early neonatal sepsis.           Methods:In a retros...