of absorbable gelatine sponge (AGS), and to find out if AGS combined with corticosteroids and/or antibiotics have an influence on these changes. Study design: Animal study Materials and Methods: Thirty-two adult guinea pigs were divided into four groups, with eight ears in each group. In control group, nothing was inserted to middle ear after traumatization of mucosa (group A). In study groups,...

The species named Alloiococcus otitis by Aguirre and Collins (1, 2) should be renamed Aloiococcus otitidis. Rule 12c of the Bacteriological Code (3) states that a specific epithet must be treated as an adjective, as a substantive in apposition in the nominative case, or as a substantive in the genitive case. "A. otitis" would belong to the second category ("otitis," the nominative case, meaning...

The purpose of this study is to examine the relation of the grade of the inflammation of the middle ear and the pathological findings of the tympanic membranes using human serial horizontal sections from 16 temporal bones with otitis media with effusion. As controls, we used 96 normal temporal bones. The results were as follows. 1) In cases with a lot of inflammation cells in the middle ear eff...

Otitis media is an infection or inflammation of the middle ear. This inflammation often begins when infections that cause sore throats, colds, or other respiratory or breathing problems spread to the middle ear. These can be viral or bacterial infections. Seventy-five percent of children experience at least one episode of otitis media by their third birthday. Almost half of these children will ...

BACKGROUND Otitis media (OM), one of the most common pediatric infectious diseases, causes inner ear inflammation resulting in vertigo and sensorineural hearing loss. Previously, we showed that spiral ligament fibrocytes (SLFs) recognize OM pathogens and up-regulate chemokines. Here, we aim to determine a key molecule derived from SLFs, contributing to OM-induced inner ear inflammation. METHO...

OBJECTIVES/HYPOTHESIS Granulocyte/macrophage colony-stimulating factor is important in the pathogenesis of acute and chronic inflammatory disease. We hypothesized that granulocyte/macrophage colony-stimulating factor plays a pivotal role in middle ear inflammation and that neutralization of granulocyte/macrophage colony-stimulating factor would inhibit neutrophil migration into the middle ear a...

vitexagnus- castus l. [vac.] has been used in the iranian traditional medicine for the treatment of pain and swelling of uterus. in this study, gc and gc/ms analyses  were carried out for the identification of essential oil chemical components. formalin and xylene-induced ear-edema were used in order to nociception and inflammation activity. then, the possible interaction between 3drugs includi...

The middle ear is the part of the ear that is enclosed behind the eardrum. A tiny tube, called the eustachian tube, drains any fluids from the middle ear into the throat. Colds and episodes of allergic runny nose, due to airborne allergens or allergies to cow’s milk or other foods, block this eustachian tube with mucus and inflammation. When this tiny mucous-membrane-lined canal is closed off, ...

The middle ear is the part of the ear that is enclosed behind the eardrum. A tiny tube, called the eustachian tube, drains any fluids from the middle ear into the throat. Colds and episodes of allergic runny nose, due to airborne allergens or allergies to cow’s milk or other foods, block this eustachian tube with mucus and inflammation. When this tiny mucous-membrane-lined canal is closed off, ...