Background: Cyclosporine A (CsA) is a nephrotoxic immunosuppressive drug. Antioxidants might attenuate its toxicity. In the present study, the effects of vitamin E and quercetin on the morphology of kidney in CsA-treated rats were investigated. Methods: Six groups of rats were used in this gavage feeding study either for 4 or 8 weeks. Groups 1 and 2 received either olive oil or 25% ethanol in o...

Background: Osteoporosis one of the postmenopausal symptoms is characterized by bone loss. There is a link between excessive reactive oxygen species (ROS) formation, estrogen deficiency due to cessation of ovarian function and bone loss. Free radicals are responsible for causing osteoblast apoptosis and reducing osteoblastogenesis in bone remodeling. Vitamin E is a potent antioxidant with the a...

Background and aim: Psoriasis is a common chronic inflammatory and proliferative disease that genetic and environmental factors have a role in its pathogenesis and duration. The objective of this study was to compare the levels of vitamin A and E in the serum of psoriasis patients and control group.Materials and methods: We evaluated 30 psoriasis patients and 30 healthy...

asthma is a chronic inflammatory airway disorder and the most common chronic disease among children characterized by frequent and chronic cough, wheezing, and dyspnea. asthma is defined as an inflammatory process in response to t- helper 2 cells. vitamin e as a lipid soluble vitamin containing 4 isomers α, β, γ, б, with α- tocopherol as the most important isomer is an important defensive agent ...

an experiment was conducted to determine of the effects of vitamin e and c supplementation in diet based on different source of oils on performance and serum parameters of broilers. a total of 320 broiler chicks (strain ross 308) used in a 2×2×2 factorial arrangement in the form of completely randomized design with eight treatments, four replicates and 10 chicks in each replicate. experimental ...

conclusions according to the results of this study, administration of vitamin e to rats counteracts the negative effects of pb on learning and memory. to more precisely extrapolate these findings to humans, future clinical studies are warranted. results the results showed that pb caused impairment in acquisition and retrieval processes in passive avoidance learning. vitamin e reversed learning ...

conclusions according to the results of this study, vitamin e probably improves the harmful effects of formaldehyde on rat kidney tissue. results comparison of the control and formaldehyde groups with the vitamin e group revealed that there were significant differences in lumen size and nuclear color of proximal tubules in rats treated by vitamin e (p < 0.05). cell degeneration, lumen size, num...

Background: Type 2 diabetes (T2D) is known as a common chronic metabolic disease worldwide. Coronary artery diseases are one of the hazardous disorders in diabetic patients. The current study aimed to investigate the relationship between dietary antioxidants intake with insulin resistance and insulin sensitivity among T2D without and with coronary stenosis (CS). Methods: This case-control study...

Background: Hyperthyroidism is associated with liver oxidative stress causing liver dysfunction in many hyperthyroid patients. The hepatoprotective effect of Satureja Khuzestanica Essential Oil (SKEO), as herbal origin antioxidant and anti-inflammatory agent on the hyperthyroidism induced hepatotoxicity and oxidative stress is investigated. Methods: Adult male sprague dawley rats were divided i...