OBSTETRICS & GYNECOLOGY Background Definition and Nomenclature Abnormal uterine bleeding associated with ovulatory dysfunction (AUB-O) (ie, oligo-ovulation or anovulation) is a spectrum of disorders most commonly associated with heavy, irregular uterine bleeding. Abnormal uterine bleeding (AUB) occurs in the setting of ovulatory dysfunction because of the effects of chronic unopposed estrogen o...