conclusions it was the first report on the blactx-m-15 gene emergence in clinical enterobacter spp. in iran. the current study demonstrated the predominant presence of the gene encoding ctx-m-15 among esbl producing enterobacter spp. commonly with a large plasmid, in the setting. background enterobacter spp. is increasingly recognized as an important nosocomial pathogen and implicated in many e...

to study the resistance to standard dosage of clopidogrel among iranian patients following percutaneous coronary intervention measured by platelet aggregation test.patients undergoing percutaneous coronary intervention in imam hussein medical center, tehran, iran, who were under treatment with aspirin, but had no history of clopidogrel usage, entered the study. patients received standard dosage...

emerging new medications in the treatment of hbv produces hope and promises for curing of hbv. over the past decade, the development of oral nucleoside/nucleotide analogs (nas) with favorable potencies and tolerabilities has led to substantial advances in chronic hepatitis b (chb) therapy. the oral anti-hbv agents currently approved are lamivudine, adefovir dipivoxil , entecavir , telbivudine, ...

background and objective: implementation of standard methods for accurate detection of bacteria, correct antibiotic susceptibility testing and effective treatment of bacterial infections play important roles in development of public health and prevention of drug resistance. this study aimed to detect bacteria using standard methods and compare the results with the results obtained in teaching h...

conclusions these results indicated that eaec strains isolated from iranian children with diarrhea were heterogeneous and showed high resistance rates against commonly used antibiotics, which was similar to that reported in studies performed in other countries. results significant percentage of local eaec strains carried the virulence plasmid genes and formed biofilms. in addition, these strain...

Genotype testing for HIV-1 drug resistance is useful for selecting antiretroviral drug regimens for patients experiencing therapeutic failure, but the optimal means for interpreting the test results is unknown because many HIV-1 protease and reverse transcriptase (RT) mutations contribute to drug resistance. This study identified common combinations of resistance mutations related to antiretrov...

background and objectives: shigella plays an important role as a causative organism of acute gastroenteritis, in children and others. rapid emergence of antibiotic resistance warrants continuous monitoring of susceptibility pattern of bacterial isolates. we report here our findings about shigella spp. isolates and their drug resistance patterns in nepalese patients. materials and methods: the s...