helicobacter pylori ( h. pylori ) infection is currently recognized as the major cause of chronic active gastritis, peptic ulcer disease and mucosa associated lymphoid tissue (malt) lymphoma and carcinoma of the stomach. eradication of the infection will prevent the recurrence of the majority of such diseases. different combined treatments have been tried in iran for eradication of h. pylori , ...

Anti-TB drugs for children: Aetiotropic therapy is used the treatment of tuberculosis (TB) in children, as well adult patients. Anti-tuberculosis (anti-TB drugs) are divided into 3 lines, taking account drug sensitivity Mycobacterium (MBT). First-line anti-TBdrugs (basic) to treat TB caused by drug-susceptible MBT. Second- and third-line (reserve) recommended MBT-induced multidrug-resistant (MD...

high-dose extended-interval dosage (hded) regimen of aminoglycosides is now considered as the standard dosage strategy in sepsis. although safety and efficacy of this dosing regimen is well studied, but new experiments show increased the risk of resistance development associated with %t>mic less than 60% of the dosing interval following extended interval dosing. moreover, limited information is...

Treatment must be initiated promptly in any patient newly diagnosed with tuberculosis. The choice for initial treatment is a regimen ideally proven in a clinical trial to have high efficacy in preventing treatment failure and relapse. Over time, the choice of this initial regimen has changed with ever increasingly efficacious and effective drug combinations. The regimen is only changed when the...

Introduction: Globally, drug-resistant tuberculosis (TB) still has a high number of cases. Pregnant women are one the high-risk populations for TB infection, especially multidrug resistance (MDR)/Rifampicin (RR) TB. Physiological differences in pregnant and safety fetus make drug treatment challenging. Case: A 20-year-old woman was 22 weeks while undergoing third month late phase short-regimen....

AIMS Multi-drug resistant Plasmodium falciparum malaria is a rapidly increasing problem in the world, particularly Thailand. Practical antimalarial regimens which are highly effective against multi-drug resistant parasites with short-term course of administration are needed. In this study, we assessed the patient compliance of a short course regimen using artemether-mefloquine. METHODS Clinic...

multidrug-resistant (mdr) and extensively drug-resistant (xdr) tuberculosis (tb) are increasing globally. treatment options for these patients are very limited. although treatment of these patients with standardized regimen is associated with high mortality and morbidity, rational usage of new drugs might be promising. in this study we will review epidemiology of xdr-tb and tdr-tb in iran and t...