نتایج جستجو برای: drug metabolism

تعداد نتایج: 792396  

Journal: :Japanese Journal of Pharmacology 1977

Journal: :Pharmacological reviews 1998
J W Lohr G R Willsky M A Acara

Journal: :Gut 1991
J M Tredger M Davis

Drug metabolism in the 1960s At the time the Liver Unit was established in 1966, interest in the study of drug metabolism was growing, stimulated largely by the pharmaceutical industry, and the legislative requirements imposed upon it. It represented a remarkable change from the situation a few years previously when'. . . the study ofthe metabolism of foreign compounds was not a popular one; bi...

Journal: :British journal of clinical pharmacology 2004
M T Kinirons M S O'Mahony

Important changes in drug metabolism occur with ageing. Age-associated reductions in function of some but not all cytochrome P450 enzymes (CYPs) have been described. Induction and inhibition of CYPs needs to be revisited in light of recent advances. The function and pharmacology of transporters have not yet been examined for an age-related effect. Finally, the concept of frailty is being underp...

Journal: :Novel Approaches in Drug Designing & Development 2017

Journal: :Journal of the Mass Spectrometry Society of Japan 2005

Journal: :research in pharmaceutical sciences 0

mucoadhesive drug delivery systems were developed to sustain drug delivery via various mucus membranes for either local or systemic delivery of poorly absorbed drugs such as peptides and proteins as well as drugs that are subjected to high first-pass metabolism. the present study was undertaken to use isolated calendula mucilage as a mucoadhesive agent and to formulate controlled release buccoa...

Journal: :Proceedings of the Royal Society of Medicine 1973

Journal: :Lab on a Chip 2021

This work demonstrates the feasibility of material-enabled oxygen scavenging in thiol-ene microchannels for on-chip subcellular drug metabolism assays under hypoxia.

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