BACKGROUND Low compliance is one of the crucial problems of contemporary psychiatry. Relapses, deterioration of cognitive functioning, negative symptoms, neuroleptic resistance are the examples of many consequences of noncompliance in schizophrenia SUBJECTS AND METHODS The study was designed to assess the compliance in the 200 patients diagnosed with paranoid schizophrenia, all in the state o...

the objective of present research was to design, evaluate and compare drug release from two different dosage forms in pulsatile drug delivery system (dds) for metoprolol tartarate (mt) as tablet and capsule. pulsatile systems are gaining a lot of interest as they deliver the drug at the right site of action at the right time and in the right amount, thus providing spatial and temporal delivery ...

OBJECTIVE To assess drug treatment compliance in institutionalised elderly patients, identifying reasons for poor compliance and introducing measures to reduce its prevalence. METHOD A programme was designed to improve drug treatment compliance in geriatric patients in residential homes. Drug intervention consisted of using an educational technique of a mixed nature (verbal information with w...

PURPOSE All current recommendations include calcium and vitamin D (Ca-D) as an integrated part of osteoporosis treatment. The purpose of this pilot study was to analyze compliance with a fixed combination of Ca-D in women persistent with the treatment. PATIENTS AND METHODS An observational study was carried out in three osteocenters in the Czech Republic. Women with osteoporosis ≥55 years of ...

OBJECTIVES To review studies on the cost consequences of compliance and/or persistence in cardiovascular disease (CVD) and related conditions (hypertension, dyslipidaemia, diabetes and heart failure) published since 1995, and to evaluate the effects of noncompliance on healthcare expenditure and the cost-effectiveness of pharmaceutical interventions. METHODS English language papers published ...

in the present investigation an attempt has been made to increase therapeutic efficacy, to reduce frequency of administration and to improve patient compliance by developing a sustained release matrix tablets of isosorbide-5-mononitrate. sustained release matrix tablets of isosorbide-5-mononitrate were developed by using different drug: polymer ratios, such in f1 (1:0.75), f2 (1:1), f3 (1:1.5),...

Views of elderly patients and their relatives on cardiopulmonary resuscitation. SIR—The results presented by Minors et al. that older subjects showed less day-today variation in life style as obtained from diary reports [1] correspond to findings revealed by compliance monitoring. This indirect assessment method, continuous electronic compliance monitoring, provides information about the actual...

In the present investigation an attempt has been made to increase therapeutic efficacy, to reduce frequency of administration and to improve patient compliance by developing a sustained release matrix tablets of isosorbide-5-mononitrate. Sustained release matrix tablets of isosorbide-5-mononitrate were developed by using different drug: polymer ratios, such in F1 (1:0.75), F2 (1:1), F3 (1:1.5),...