Transdermal scopolamine may be used to reduce drooling in children with disabilities. Side-effects include dilated pupils and a reduction in the near point of accommodation (the closest point at which clear vision is possible). Two male children with epilepsy, one with spinal dysraphism (aged 7y 6mo) and one with cerebral palsy (aged 5y 8mo), who have undergone treatment for drooling with trans...

Many persons with severe and profound disabilities exhibit chronic and excessive drooling, which can have unfavorable effects on their socialization and health. Few treatments to reduce this behavior, however, have been evaluated systematically. In the present investigation, oral motor stimulation was used with 2 children who attended a residential educational facility for students who are blin...

OBJECTIVE To determine the 9 month period effect of botulinum toxin A (BoNT-A) injection into the salivary gland in children with neurologic disorders and sialorrhea by qualified parent/caregiver-administered questionnaires. METHOD A total of 17 patients (age 7.6±4.24 years) were enrolled in this study. The degree of sialorrhea was assessed at the baseline, 2 weeks, 1, 2, 4, 6 and 9 months af...

OBJECTIVES To introduce a technical modification for interruption of the parotid and submandibular salivary ducts and to demonstrate the technique's effectiveness and effect on quality of life. DESIGN Retrospective, uncontrolled, consecutive case series. SETTING A tertiary care pediatric otolaryngology practice. PATIENTS Eighteen drooling and aspirating children. INTERVENTION Transoral ...

Patients given a more soluble inhaled anesthetic usually take longer to awaken from anesthesia than do patients given a less soluble anesthetic. In the present study, we tested whether such a delay in awakening was also associated with a delay in restoration of protective airway reflexes. Patients were randomly assigned to receive desflurane (n = 31) or sevoflurane (n = 33) via a laryngeal mask...

PURPOSE To investigate the effect of botulinum toxin type A (BTX-A; Botox) in reducing saliva in patients with Parkinsonism. METHODS Fifteen patients with clinical diagnosis of idiopathic Parkinson's disease, dementia with Lewy bodies, or multiple system atrophy were enrolled in this open clinical trial. A total of 40-unit dose of Botox was injected into the bilateral parotid and submandibula...

OBJECTIVE The aim of the current study was to carry out a preliminary validation of devices for standardized collection of whole mouth fluid (WMF) in comparison to the passive drooling method for protein analysis in healthy subjects. MATERIALS AND METHODS A carefully designed sample collection/pretreatment protocol is crucial to the success of any saliva proteomics project. In this study, WMF...

A 4-year-old previously healthy and fully immunized boy presents with a 2-day history of sore throat and a 1-day history of fever and drooling. He awakened today with worsening sore throat, drooling, and subjective fever. He complains of pain during swallowing and refuses oral intake. He has no cough, congestion, sick contacts, or recent travel. His prenatal, natal, and postnatal histories cont...

OBJECTIVE To review and assess the current published literature regarding the efficacy of surgical management of sialorrhea in pediatric patients. DATA SOURCES The MEDLINE database was systematically reviewed for articles reporting on the use of surgical procedures to treat sialorrhea published from January 1, 1963, to November 30, 2008. STUDY SELECTION Inclusion criteria included presence ...