For more than two decades, the cheetah (Acinonyx jubatus) has been considered a paradigm of disease vulnerability associated with low genetic diversity, particularly at the immune genes of the major histocompatibility complex (MHC). Cheetahs have been used as a classic example in numerous conservation genetics textbooks as well as in many related scientific publications. However, earlier studie...

Mohammad Reza Danesh Impact Laboratory, DRB –101 Dept. of Aerospace and Mechanical Engineering University of Southern California Los Angeles, California 90089-1111, USA Tel: (213) 740-9621, Fax: (213) 740-6668 [email protected] Yan Jin Impact Laboratory, DRB –101 Dept. of Aerospace and Mechanical Engineering University of Southern California Los Angeles, California 90089-1111, USA Tel: (213) 740...

Neoplastic mouse lung epithelial cells contain greatly diminished activity, protein, and mRNA for the type I isozyme of cyclic AMP-dependent protein kinase (PKA I), while expression of the type II isozyme (PKA II) is similar to that of normal lung cells. A time course of PKA mRNA content in transcriptionally inhibited cells indicated that most PKA mRNAs are more stable in the neoplastic E9 cell...

We hypothesize that immune responses that develop following immunotherapy, particularly in patients with objective responses, are directed against a wide range of antigenic determinants. However, in the absence of autologous tumor cells, monitoring is frequently limited to a small number of well-defined tumor-associated antigens (TAA) and underestimates the immune response. Further, we hypothes...

Protistan bacterivory, a microbial process involving ingestion and digestion, is ecologically important in the microbial loop in aquatic and terrestrial ecosystems. While bacterial resistance to protistan ingestion has been relatively well understood, little is known about protistan digestion in which some ingested bacteria could not be digested in cells of major protistan grazers in the natura...

Ninety-six crossbred steers were used in a 172-d feedlot growth performance trial to determine the effects of type processing on the comparative feeding value of barley in a 90% concentrate finishing diet. Treatments were: 1) steam-flaked corn (SFC; density = .31 kg/L); 2) dry-rolled barley (DRB; density = .39 kg/L); 3) steam-rolled barley, coarse roll (SRB-C, density = .39 kg/L); and 4) SRB, t...

The common marmoset (Callithrix jacchus) is a New World primate species that is highly susceptible to fatal infections caused by various strains of bacteria. We present here a first step in the molecular characterization of the common marmoset's Mhc class II genes by nucleotide sequence analysis of the polymorphic exon 2 segments. For this study, genetic material was obtained from animals bred ...

Major histocompatibility complex (MHC) class II DRB genotypes were examined in two geographically isolated populations of California sea lions (Zalophus californianus) (Gulf of California and California coastal Pacific Ocean). Genomic DNA from 227 California sea lions was examined using eight sequence-specific primer (SSP) pairs flanking the putative peptide-binding site. A total of 40 differen...

A ocorrência de diarreia e doença respiratória bovina (DRB) em bezerras resulta impactos econômicos, reprodutivos produtivos. O objetivo deste trabalho foi analisar o impacto da DRB no desenvolvimento das produção leiteira futura. utilizou dados retrospectivos fazenda localizada Carambeí-PR. Todos os foram coletados fêmeas bovinas raça Holandesa, nascidas entre novembro 2017 a 2018, sendo que e...