BACKGROUND Currently available tools for identifying individuals at high risk of type 2 diabetes can be invasive, costly and time consuming. This study aims to develop and validate a self-assessment tool for identifying individuals at high risk of type 2 diabetes in the Chinese general population. METHODS A cross-sectional survey was conducted from 2000 to 2001 in a nationally representative ...

OBJECTIVE To propose Irish CT diagnostic reference levels (DRLs) by collecting radiation doses for the most commonly performed CT examinations. METHODS A pilot study investigated the most frequent CT examinations. 40 CT sites were then asked to complete a survey booklet to allow the recording of CT parameters for each of 9 CT examinations during a 12-week period. Dose data [CT volume index (C...

Differential reinforcement of low rate responding (DRL) can be defined as withholding reinforcement until probability of a target behaviour has decreased to a particular criterion. Typically, the DRL lowers the overall rate of a specific target response by incrementally increasing the time interval between responses and delivering reinforcement contingent upon a response occurring at or above t...

In Sweden the use of daytime running lights (DRL) was made mandatory on 1 October 1977 for all motor vehicles at once, during all seasons and for all areas. According to a study conducted by Andersson and Nilsson (1981) [Andersson and Nilsson. VTI Swedish Road and Transport Research Institute, Report No. 208A; 1981] the introduction of DRL resulted in a reduction of 11% of multiple accidents du...

Background  It is remain a main concern that pediatric chest radiographies contribute to the significant radiation exposure to the thyroid gland as a more susceptible organ to radiation induced cancer. The aim of this study was to evaluate the entrance surface dose (ESD) of pediatric chest radiography compared to the diagnostic reference levels (DRL) and evaluation the efficacy of the lead (Pb)...

Differential reinforcement of low rate responding (DRL) can be defined as withholding reinforcement until probability of a target behaviour has decreased to a particular criterion. Typically, the DRL lowers the overall rate of a specific target response by incrementally increasing the time interval between responses and delivering reinforcement contingent upon a response occurring at or above t...

The molecular program controlling hematopoietic differentiation is not fully understood. Here, we describe a family of zebrafish genes that includes a novel hematopoietic regulator, draculin-like 3 (drl.3). We found that drl.3 is expressed in mesoderm-derived hematopoietic cells and is retained during erythroid maturation. Moreover, drl.3 expression correlated with erythroid development in gata...

Preclinical Research N-methyl-D-aspartate (NMDA) receptor antagonists, such as ketamine, have emerged as novel candidate treatments for major depressive disorder, but abuse potential of these agents is a concern. The NMDA antagonist phencyclidine has known abuse liability but undefined efficacy as an antidepressant. To further evaluate the relationship between antidepressant-like and abuse-rela...

Several compounds were tested on the differential-reinforcement-of-low-rate 72-sec (DRL 72-sec) schedule, a behavioral screen to determine putative antidepressants; these compounds were evaluated in two outbred stocks of rats, Harlan and Holtzman Sprague-Dawley rats. A dose-response determination for the tricyclic antidepressants, imipramine and desipramine, the selective serotonin (5-hydroxytr...

Background: Multislice CT Scan (MSCT) brain examination in pediatric cases should pay attention to the lowest possible dose but still provide optimal anatomical information. Pediatric has a higher risk of developing cancer compared adults who receive same dose. The purpose this study is obtain value use Adaptive Statistical Iterative Reconstruction (ASIR)-V technique with variations tube curren...